Evidence map›Paper›PMID 39623612›Full record

ArticleAnnals of dermatology2024

Clinical Manifestation of Alopecia Areata After COVID-19 Infection or Vaccination.

Seungjin Son, Soyoung Jin, Ji Yeon Hong, Jung-Min Shin, Kyung Eun Jung, Young-Joon Seo, Chang-Deok Kim, Dongkyun Hong, Young Lee

Abstract read
In one paragraph

Article in Annals of dermatology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Seungjin SonDepartment of Dermatology, Chungnam National University School of Medicine, Daejeon, Korea.ORCID https://orcid.org/0000-0001-8243-1389
Soyoung JinDepartment of Dermatology, Chungnam National University School of Medicine, Daejeon, Korea.ORCID https://orcid.org/0009-0006-2508-4564
Ji Yeon HongDepartment of Dermatology, Chungnam National University School of Medicine, Daejeon, Korea.ORCID https://orcid.org/0000-0002-5632-8449
Jung-Min ShinDepartment of Dermatology, Chungnam National University School of Medicine, Daejeon, Korea.ORCID https://orcid.org/0000-0001-7465-5243
Kyung Eun JungDepartment of Dermatology, Chungnam National University School of Medicine, Daejeon, Korea.ORCID https://orcid.org/0000-0003-0968-1079
Young-Joon SeoDepartment of Dermatology, Chungnam National University School of Medicine, Daejeon, Korea.ORCID https://orcid.org/0000-0002-4955-590X
Chang-Deok KimDepartment of Dermatology, Chungnam National University School of Medicine, Daejeon, Korea.ORCID https://orcid.org/0000-0001-9341-6491
Dongkyun Hong *Department of Dermatology, Chungnam National University School of Medicine, Daejeon, Korea. chupee@hanmail.net.ORCID https://orcid.org/0000-0002-4244-0691
Young Lee *Department of Dermatology, Chungnam National University School of Medicine, Daejeon, Korea. resina20@cnu.ac.kr.ORCID https://orcid.org/0000-0001-9205-1785

Funding

Chungnam National University Hospital
6 · The paper itself

Abstract

backgroundAlopecia areata (AA) is characterized by an autoimmune inflammatory response to hair follicles. Several studies have suggested that infection and vaccination can trigger an autoimmune process around hair follicles. Moreover, reports of AA and various other autoimmune diseases have increased since the coronavirus disease 2019 (COVID-19) pandemic became established.

objectiveWe assessed the clinical characteristics and treatment response in patients who developed AA following COVID-19 infection or vaccination.

methodsThis retrospective study involved patients who had developed COVID-19 or received a COVID-19 vaccination within 3 months before the onset or aggravation of AA from January 2020 to December 2022.

resultsFifty patients met the inclusion criteria. Eighteen patients had a history of COVID-19 infection, and 32 had a history of COVID-19 vaccination. The mean onset of AA after COVID-19 infection and vaccination was 5.22±3.35 and 4.13±2.73 weeks, respectively. The most common COVID-19-associated symptoms before AA were fever (88.9%) in the infection group and myalgia (50.0%) in the vaccination group. In the vaccination group, AA most commonly occurred after receiving the Pfizer-BioNTech vaccine (BNT162b2, 46.9%) or Moderna vaccine (mRNA-1273, 34.4%). The vaccination group showed more rapid improvement than the infection group; however, both showed significant improvement after 6 months of treatment of AA.

conclusionWe examined the clinical characteristics and treatment responses of patients who developed AA after COVID-19 infection or vaccination. Further research is needed to evaluate the detailed pathogenesis and association between COVID-19 and AA.

Indexed as

Alopecia areataAutoimmune diseasesCOVID-19InfectionVaccination

Identifiers

PMID39623612
PMCPMC11621643

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.