Evidence map›Paper›PMID 39623586›Full record

ArticleParasitology2024

Expression and serodiagnostic efficacy of a novel echinococcosis-specific recombinant fusion antigen rAgB8/1-Em18-Eg95.

Yang Xianwei, Wang Tao, Chen Yin, Wang Wentao

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Parasitology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Yang XianweiDepartment of Thyroid Surgery, Sichuan Provincial People's Hospital, University of Electronic Science and Technology of China, Chengdu, 610041, P.R China.ORCID 0000-0001-8696-4844
Wang TaoDepartment of Liver Surgery, West China Hospital, Sichuan University, Chengdu 610041, P. R. China.
Chen YinDepartment of Hepatobiliary Surgery, Ganzi Tibetan Autonomous Prefecture People's Hospital, Kangding, Sichuan 626000, P. R. China.
Wang WentaoDepartment of Liver Surgery, West China Hospital, Sichuan University, Chengdu 610041, P. R. China.ORCID 0000-0002-6966-2665

Funding

National Outstanding Youth Science Fund Project of National Natural Science Foundation of China 82202548
6 · The paper itself

Abstract

Echinococcosis lacks sensitive serological diagnostic tools. The echinococcosis-specific antigens Eg95, AgB8/1 and the Em18 gene sequences were fused and expressed as the novel recombinant antigens rAgB8/1-Em18-Eg95 (T3) and rEm18-Eg95 (T2), used for the diagnosis of hydatid disease, prepared into an enzyme-linked immunosorbent reaction (ELISA) kit, and evaluated for their serological diagnostic value. The relative molecular weight of the T3 protein was 88.1 kDa, the purified concentration was 1.5 mg mL

Indexed as

Antigens, HelminthEchinococcosisHelminth ProteinsAnimalsAntibodies, HelminthEchinococcus granulosusEnzyme-Linked Immunosorbent AssayFemaleHumansRecombinant Fusion ProteinsSensitivity and SpecificitySerologic TestsAntibodies, HelminthAntigens, HelminthHelminth ProteinsRecombinant Fusion ProteinsAgB8/1diagnosisechinococcosisEg95Em18

Identifiers

PMID39623586
PMCPMC12052424

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.