Observational studyBMC musculoskeletal disorders2024
Association between obesity measurement indexes and symptomatic knee osteoarthritis among the Chinese population: analysis from a nationwide longitudinal study.
Observational study in BMC musculoskeletal disorders, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.
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Who cites it
10 citing papers in PubMed.
- Association of dynapenic abdominal obesity with prevalence and incidence of symptomatic knee osteoarthritis among the middle-aged and older Chinese.Aging clinical and experimental research · 2026Article
- Article
- Dynapenic abdominal obesity and symptomatic knee osteoarthritis: results from a large cross-sectional study of middle-aged and older adults in China.Annals of joint · 2026Article
- Synergistic effects of body fat percentage and C-reactive protein triglyceride-glucose index on cardiovascular disease risk: a Chinese cohort study.Scientific reports · 2025Article
- Evaluating anthropometric indices of obesity for early osteoarthritis detection: focus on body fat percentage and relative fat mass.Clinical rheumatology · 2025Article
- Association of eight anthropometric indexes related to obesity with the prevalence of clinical osteoarthritis among American adults: a national cross-sectional study.European journal of medical research · 2025Article
- Burden of knee osteoarthritis in China and globally: 1990-2045.BMC musculoskeletal disorders · 2025Article
- Association between obesity indices, insulin resistance markers, and osteoarthritis in middle-aged and elderly Chinese adults.Frontiers in nutrition · 2025Article
- Association between BMI and knee osteoarthritis in Chinese adults aged 45 years and older: evidence from the 2021 Global Burden of Disease analysis and the China Health and Retirement Longitudinal Study.Frontiers in public health · 2025Article
- Body roundness index and the risk of knee osteoarthritis: evidence from the China Health and Retirement Longitudinal Study.Frontiers in nutrition · 2025Article
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Abstract
backgroundThe current literature lacks robust clinical data and evidence delineating the relationship between obesity measurement indexes and knee osteoarthritis (KOA). Consequently, this investigation seeks to elucidate the potential link between obesity measurement indexes and KOA among Chinese adults in a nationally representative study.
methodsFirstly, this research performed an observational study in the China Health and Retirement Longitudinal Study (CHARLS). The variables were extracted from interviews and compared between KOA and non-KOA participants. The relationship between obesity measurement indexes and KOA was analyzed by multivariate logistic regression. Restricted cubic spline (RCS) regression tests the nonlinearity of the relationship between obesity measurement indexes and KOA. Subgroup analyses were performed by sex to verify the robustness of the findings.
resultsIn this cross-sectional analysis, we found a positive association between obesity measurement indexes and KOA. These results did not change on multiple imputations(BMI: OR = 1.02, 95% CI, 1.01-1.04, P < 0.05; WHtR: OR = 2.85, 95% CI, 1.08-7.51, P < 0.05; BRI: OR = 1.07, 95% CI, 1.01-1.12, P < 0.05; BFP: OR = 1.02 95% CI, 1.00-1.03, P < 0.05). All the effects of obesity measurement indexes with KOA are present in females. None of the stratifying variables significantly affected the association between obesity measurement indexes and KOA. RCS regression test revealed the linear positive correlation between obesity measurement indexes and KOA.
conclusionIn this cross-sectional study, we found a significant association between obesity measurement indexes and KOA. This relationship is not affected by stratification and confounding factors.
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