ArticleBMC public health2024
Association between composite dietary antioxidant index and erectile dysfunction: a cross-sectional study from NHANES.
Article in BMC public health, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.
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Who cites it
2 citing papers in PubMed.
- Assessing the Impact of Composite Dietary Antioxidant Index on Gastric Cancer Risk: A Case-Control Study in Southeast China.Nutrients · 2025Article
- Associations of dietary inflammatory index and composite dietary antioxidant index with erectile dysfunction and the mediating role of metabolic dysregulation: a cross-sectional analysis of NHANES 2001-2004 data.Frontiers in nutrition · 2025Article
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Authors and funding
7 authors.
Funding
Abstract
backgroundIndividual antioxidants may not fully capture the comprehensive antioxidant intake from an individual's diet. This study utilizes the Complex Dietary Antioxidant Index (CDAI) to evaluate the combined effects of various dietary antioxidants in the diet. The goal is to investigate the relationship between CDAI and the incidence of erectile dysfunction (ED), offering insights for dietary guidelines and intervention strategies aimed at mitigating the burden of ED.
methodsThis cross-sectional study utilized data from the National Health and Nutrition Examination Survey (NHANES) database in the years 2001-2004. We employed a weighted multivariate logistic regression model to validate the relationship between CDAI and ED. Subgroup analyses were conducted to explore the correlation between CDAI and ED across different subgroups. Additionally, we used propensity score matching (PSM) to adjust for several key confounding variables, enhancing the robustness of the results.
resultsIn the fully adjusted multivariate logistic regression model for confounding variables, CDAI is negatively correlated with the risk of ED (OR = 0.95, 95% CI: 0.92-0.99, P = 0.005). When CDAI is transformed into a categorical variable based on quartiles, Q3 (OR = 0.73, 95% CI: 0.53-0.99, P = 0.040) and Q4 (OR = 0.70, 95% CI: 0.51-0.96, P = 0.026) show a negative correlation with the risk of ED. Subgroup analysis reveals no significant interaction. After adjusting for major confounding variables through PSM, the association between CDAI and reduced risk of ED remains significant.
conclusionIn our study cohort, there is an association between CDAI and a reduced risk of ED, and further research is needed to validate and refine this conclusion.
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