Evidence map›Paper›PMID 39623263›Full record

ArticleNan fang yi ke da xue xue bao = Journal of Southern Medical University2024

[Neuronal plasticity changes in the central amygdala and prelimbic cortex network in mice with chronic unpredictable mild stress-induced depression].

D Liu, Z Chen, Y Wang, X Li, P Zhao, H Zheng

Abstract readEnglish Abstract
In one paragraph

Article in Nan fang yi ke da xue xue bao = Journal of Southern Medical University, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

D LiuSchool of Basic Medicine, Bengbu Medical University, Bengbu 233030, China.
Z ChenSchool of Clinical Medicine, Bengbu Medical University, Bengbu 233030, China.
Y WangSchool of Clinical Medicine, Bengbu Medical University, Bengbu 233030, China.
X LiSchool of Clinical Medicine, Bengbu Medical University, Bengbu 233030, China.
P ZhaoSchool of Clinical Medicine, Bengbu Medical University, Bengbu 233030, China.
H ZhengSchool of Clinical Medicine, Bengbu Medical University, Bengbu 233030, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveTo explore the relationship between alterations of neural network plasticity and spatial learning and memory functions in mouse models with depression-like behaviors.

methodsC57Thy1-YFP/GAD67-GFP mice were randomized into control group (with no treatment) and chronic unpredictable mild stress (CUMS) group (

resultsCompared with the control mice, CUMS mice showed significantly decreased sucrose preference, total distance moved, number of grid-crossings, entries into the central area, and time spent in the central area in the open field test (

conclusionCUMS-induced depression may lead to plastic changes in the excitatory and inhibitory neuronal networks within the CeA and PrL to cause impairment of spatial learning and memory abilities in mice.

Indexed as

DepressionNeuronal PlasticityStress, PsychologicalAnimalsBehavior, AnimalCentral Amygdaloid NucleusDisease Models, AnimalMaleMaze LearningMemoryMiceMice, Inbred C57BLNeuronsPrefrontal Cortexamygdaladepressionmedial prefrontal cortexneuroplasticity

Identifiers

PMID39623263
PMCPMC11605193

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.