SynthesisClinical oral investigations2024
Effect of the reduction in the exposure time to at-home bleaching gel on color change and tooth sensitivity: A systematic review and meta-analysis.
Synthesis in Clinical oral investigations, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
4 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Interventions for bleaching-induced tooth sensitivity: an umbrella review.Frontiers in oral health · 2026Pooled it
- Evaluating the Efficiency and Tooth Sensitivity of a Novel Whitening Strip: A Randomized, Double-Blind Controlled Trial.Journal of esthetic and restorative dentistry : official publication of the American Academy of Esthetic Dentistry ... [et al.] · 2026Trial
- Bleaching with biocatalysts and violet LED: a randomized clinical trial using a hybrid design with parallel-group and split-mouth approaches : Violet LED and biocatalysts in in-office whitening: a split-mouth trial.Clinical oral investigations · 2025Trial
- Clinical myths in dental bleaching: an evidence-based structured narrative review.Brazilian oral research · 2026Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors.
Funding
Abstract
objectiveTo investigate the effect of reducing exposure time to at-home bleaching gel on color change and tooth sensitivity. MATERIALS AND
methodsThe search was carried out using PubMed, Scopus, Web of Science, EMBASE, LILACS, Cochrane. Randomized clinical trials (RCTs) were included involving adult patients who have never undergone bleaching treatment before (P), subjected to bleaching with a reduced exposure time to the at-home bleaching agent (I) compared to those who used it for the time indicated by the manufacturer (C), to evaluate the effects on color change and tooth sensitivity (O). The Cochrane guidelines for the Risk of Bias Assessment Tool (RoB 2.0) and GRADE were used to assess risk of bias and quality of evidence, respectively.
resultsUsing at-home bleaching gel for the period recommended by the manufacturer resulted in significantly higher ΔE
conclusionsReducing exposure time to at-home bleaching gel reduces tooth sensitivity events; however, most of the parameters that assess color change indicate using at-home bleaching gel for the time recommended by the manufacturer. CLINICAL SIGNIFICANCE: Reducing exposure time to at-home bleaching gel should be applied with caution in clinical practice. Although the evidence suggests a reduction in tooth sensitivity events, bleaching effectiveness was significantly higher after using the bleaching gel for the time indicated by the manufacturer.
Indexed as
Identifiers
39623180What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.