Evidence map›Paper›PMID 39622826›Full record

ArticleScientific reports2024

Increased risk of open angle glaucoma in patients with moyamoya disease from a nationwide population-based cohort in Korea.

Min Seok Kim, Eun Ji Lee, Si Un Lee, Tae-Woo Kim, Sang Jun Park, Se Joon Woo, Jeongwoo Lee, Seonghee Nam, Kwangsic Joo

Abstract read
In one paragraph

Article in Scientific reports, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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0citing papers in PubMed
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1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Min Seok KimDepartment of Ophthalmology, Seoul National University College of Medicine, Seoul National University Bundang Hospital, Seongnam, South Korea.
Eun Ji LeeDepartment of Ophthalmology, Seoul National University College of Medicine, Seoul National University Bundang Hospital, Seongnam, South Korea.
Si Un LeeDepartment of Neurosurgery, Seoul National University College of Medicine, Seoul National University Bundang Hospital, Seongnam, South Korea.
Tae-Woo KimDepartment of Ophthalmology, Seoul National University College of Medicine, Seoul National University Bundang Hospital, Seongnam, South Korea.
Sang Jun ParkDepartment of Ophthalmology, Seoul National University College of Medicine, Seoul National University Bundang Hospital, Seongnam, South Korea.
Se Joon WooDepartment of Ophthalmology, Seoul National University College of Medicine, Seoul National University Bundang Hospital, Seongnam, South Korea.
Jeongwoo LeeData research, Samil Pharm Co. LTD, Seoul, South Korea.
Seonghee NamData research, Samil Pharm Co. LTD, Seoul, South Korea.
Kwangsic JooDepartment of Ophthalmology, Seoul National University College of Medicine, Seoul National University Bundang Hospital, Seongnam, South Korea. namooj@snu.ac.kr.

Funding

Ministry of Science and ICT, South Korea 2022R1A2C4002114Ministry of Science and ICT, South Korea,South Korea RS-2023-00210974Seoul National University Bundang Hospital 02-2023-0037
6 · The paper itself

Abstract

This nationwide population-based retrospective cohort study aims to investigate the association between Moyamoya disease (MMD) and open-angle glaucoma (OAG). In this study using the Korean National Health Insurance Service database, a total of 36,432 patients having diagnostic code with MMD between 2002 and 2022, and their age-, sex-matched non-MMD controls (n = 346,769) were included. We used a Cox proportional hazard model to determine the association between MMD and subsequent OAG after excluding cases with preexisting diagnosis of MMD for the initial 2-year. Kaplan-Meier survival analyses with log-rank test were performed to compare the incidence probability of OAG based on the MMD diagnosis. Cox regression analysis showed that the diagnosis of MMD was associated with increased risk of subsequent diagnosis of OAG (adjusted HR, 1.26; 95% CI, 1.14-1.38; P < 0.001). The cumulative incidence probability of OAG was 3.7% in MMD group and 2.9% in control group at the end of the study period, and was significantly higher among MMD patients than controls consistently during the study period (P < 0.001).In conclusion, the nationwide longitudinal data of Korean population revealed a significant association between MMD and OAG. Presence of MMD may increase the risk of developing OAG.

Indexed as

Glaucoma, Open-AngleMoyamoya DiseaseAdolescentAdultAgedFemaleHumansIncidenceKaplan-Meier EstimateMaleMiddle AgedProportional Hazards ModelsRepublic of KoreaRetrospective StudiesRisk FactorsYoung AdultGlaucomaMoyamoya diseaseRisk factor

Identifiers

PMID39622826
PMCPMC11612201

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