ArticleAllergy, asthma & immunology research2024
Association Between Triglyceride-Glucose Index and Development of Asthma in US Adolescents: A Cross-Sectional Study.
Article in Allergy, asthma & immunology research, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.
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Who cites it
7 citing papers in PubMed.
- Association Between C-Reactive Protein-Triglyceride Glucose Index and All-Cause Mortality and Exacerbation in Adult Asthma: NHANES, 1999-2010 and 2015-2018.Allergy, asthma & immunology research · 2026Article
- Association between the C-reactive protein-triglyceride-glucose index and asthma risk: evidence from the NHANES cohort and validation in the CHNS cohort.Clinics (Sao Paulo, Brazil) · 2026Article
- Association of TyG-BMI and genetic risk with incident adult-onset asthma: Insights from the UK biobank.Chinese medical journal · 2026Article
- Associations between C-reactive protein-triglyceride glucose index and asthma risk among Chinese adults: evidence from the CHARLS cohort and external hospital-based validation.Frontiers in immunology · 2026Article
- Inflammatory-metabolic alterations in asthma-COPD overlap compared with COPD: evidence from NHANES and a hospital-based cohort.Frontiers in medicine · 2026Article
- Association between insulin resistance and multiple chronic diseases: a cross-sectional study from CHARLS.Journal of health, population, and nutrition · 2025Article
- Non-T2 asthma.Current opinion in pulmonary medicine · 2025Review
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Authors and funding
2 authors.
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Abstract
purposeMetabolic abnormalities, such as insulin resistance (IR) and dyslipidemia, have been linked to an increased risk of asthma. The triglyceride-glucose index (TyG), a metric indicating metabolic dysfunction, exhibits correlations with metabolic syndrome and IR. However, little research has been conducted on the relationship between TyG and asthma in the pediatric population. Therefore, we aimed to investigate the relationship between TyG and asthma among adolescents.
methodsData from the National Health and Nutrition Examination Survey between 2007 and 2012 was analyzed in this cross-sectional study. The association between TyG and asthma was evaluated using various statistical methods, including multivariate logistic regression analysis, restricted cubic spline (RCS) analysis, threshold effects analysis, and subgroup analysis.
resultsA total of 1,629 adolescent participants were enrolled in the study, consisting of 878 (53.9%) males and 751 females (46.1%), with a mean age of 15.5 years. After adjusting for all covariates in the multivariate logistic regression, the adjusted odds ratio (OR) for TyG and asthma in the highest quintile (Q5, > 8.65) was 4.26 (95% confidence interval [CI], 1.54, 11.81;
conclusionsIn US adolescents, a U-shaped association was observed between asthma and the TyG, with a critical turning point identified at around 7.78.
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