Evidence map›Paper›PMID 39622684›Full record

ReviewAllergy, asthma & immunology research2024

Revisiting T Cells in Chronic Rhinosinusitis.

Sungmin Moon, Min-Seok Rha

Abstract readReview
In one paragraph

Review in Allergy, asthma & immunology research, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Review
  2. Review
  3. Review
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Sungmin MoonDepartment of Otorhinolaryngology, Yonsei University College of Medicine, Seoul, Korea.ORCID https://orcid.org/0000-0002-1142-2079
Min-Seok RhaDepartment of Otorhinolaryngology, Yonsei University College of Medicine, Seoul, Korea. msrha@yuhs.ac.ORCID https://orcid.org/0000-0003-1426-7534

Funding

Ministry of Health and Welfare HI23C1464National Research Foundation of Korea 2022M3A9D3016848
6 · The paper itself

Abstract

A variety of immune cells in the nasal tissue are involved in the immunopathogenesis of chronic rhinosinusitis (CRS), a chronic inflammatory disease affecting the nasal cavity and paranasal sinuses. T cells play a pivotal role in orchestrating immune dysregulation in CRS by producing key cytokines. Recent studies have expanded the understanding of T cell biology across the inflammatory endotypes of CRS. This review summarizes current knowledge on the multifaceted roles of T cells in the pathophysiology of CRS. Particularly, we highlight the alterations in phenotypes and functions of various T cell subsets in CRS. Additionally, as functional studies of effector and regulatory T cell populations have revealed potential translational targets, we suggest perspectives for future research into T cell-oriented therapeutic strategies for CRS.

Indexed as

nasal mucosaparanasal sinusespathophysiologyRhinosinusitisT-lymphocytes

Identifiers

PMID39622684
PMCPMC11621483

What OpenQuestion holds

Textmetadata
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.