Evidence map›Paper›PMID 39622622›Full record

ArticleLife science alliance2025

ciBAR1 loss in mice causes laterality defects, pancreatic degeneration, and altered glucose tolerance.

Eunice N Kim, Feng-Qian Li, Ken-Ichi Takemaru

Abstract read
In one paragraph

Article in Life science alliance, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Eunice N KimMolecular and Cellular Biology Graduate Program, Stony Brook University, Stony Brook, NY, USA.ORCID 0000-0002-6869-3099
Feng-Qian LiDepartment of Pharmacological Sciences, Stony Brook University, Stony Brook, NY, USA.
Ken-Ichi TakemaruMolecular and Cellular Biology Graduate Program, Stony Brook University, Stony Brook, NY, USA ken-ichi.takemaru@stonybrook.edu.ORCID 0000-0001-9657-9966

Funding

Trafficking and Sorting Mechanisms of Golgi Vesicles to CiliaR01DK123641 · NIDDK · STATE UNIVERSITY NEW YORK STONY BROOK · PI TAKEMARU, KEN-ICHI · 2020 to 2023
$1.4M
Chibby and Its Associated Proteins in Ciliated Cell DifferentiationR01HL139643 · NHLBI · STATE UNIVERSITY NEW YORK STONY BROOK · PI TAKEMARU, KEN-ICHI · 2018 to 2020
$1.2M
Elucidating the Roles of the Membrane-Binding Proteins ciBAR1 and ciBAR2 in CiliogenesisF31HL168828 · NHLBI · STATE UNIVERSITY NEW YORK STONY BROOK · PI KIM, EUNICE NA YOUNG · 2023 to 2025
$123k
NHLBI NIH HHS F31 HL168828NHLBI NIH HHS R01 HL139643NIDDK NIH HHS R01 DK123641
6 · The paper itself

Abstract

Bin/Amphiphysin/Rvs (BAR) domains are highly conserved domains found in all eukaryotes. BAR domain proteins form crescent-shaped dimers that sense and sculpt curved lipid membranes and play key roles in various cellular processes. However, their functions in mammalian development are poorly understood. We previously demonstrated that Chibby1-interacting BAR domain-containing 1 (ciBAR1, formerly known as FAM92A) localizes to the ciliary base and plays a critical role in ciliogenesis. Here, we report ciliopathy phenotypes of

Indexed as

CiliaMice, KnockoutPancreasAnimalsFemaleGlucose IntoleranceMaleMiceMice, Inbred C57BLPhenotype

Identifiers

PMID39622622
PMCPMC11612972

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.