ArticleBMJ open2024
Can oral cancer screening reduce late-stage diagnosis, treatment delay and mortality? A population-based study in Taiwan.
Article in BMJ open, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.
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Who cites it
10 citing papers in PubMed.
- Article
- Predictors of Lesion Detection in a 12-Year Oral Cancer Screening Program: A Cohort Study in Northern Portugal.Journal of oral pathology & medicine : official publication of the International Association of Oral Pathologists and the American Academy of Oral Pathology · 2026Article
- Multimodal oral cancer detection with embedding-level oversampling of fused image and clinical data.Scientific reports · 2026Article
- Salivary CD5L as a Potential Non-Invasive Biomarker for Pathological Staging and Prognostic Assessment in Oral Squamous Cell Carcinoma.Diagnostics (Basel, Switzerland) · 2026Article
- ENOX2 (tNOX)-Associated Stemness in Oral Cancer Cells and Its Clinical Correlation in Head and Neck Tumors.Antioxidants (Basel, Switzerland) · 2026Article
- Salivary biomarkers in oral cancer diagnosis: advancing conventional treatment strategies.Military Medical Research · 2026Review
- Patient-related factors influencing delays in oral cancer diagnosis: Insights from Pakistan.Journal of dental sciences · 2026Article
- Nationwide oral cancer screening and rural-urban disparities in oral cancer diagnosis, treatment and mortality: a population-based cohort study in Taiwan.BMJ public health · 2026Article
- Place vs. Pocketbook: Associations of Area-Level and Individual-Level Income on Oral Cavity Cancer Late-Stage Diagnosis.Cancer medicine · 2025Article
- Loss of ZC3H12A Expression Is Linked to Higher Mortality Risk and Increased Lymphatic Metastasis in Oral Squamous Cell Carcinoma.In vivo (Athens, Greece)Article
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3 authors.
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Abstract
objectiveThis study evaluates the effectiveness of Taiwan's nationwide oral cancer screening programme in reducing late-stage diagnosis, treatment delays and mortality.
designA retrospective cohort study was conducted.
settingThe study utilized Nationally representative datasets, including the Cancer Registry, Oral Mucosal Screening and National Health Insurance databases in Taiwan.
participantsThe study included patients with oral cancer diagnosed between 1 January 2010 and 31 December 2013, with follow-up through 31 December 2018. The final analysis included 16 430 patients.
interventionThe intervention was Taiwan's nationwide oral cancer screening programme which provides visual inspection and palpation of the oral mucosa. PRIMARY OUTCOME MEASURES: The primary outcomes measured were late-stage diagnosis (stages III and IV), treatment delay (time from diagnosis to treatment >30 days) and all-cause mortality.
resultsOral cancer screening was statistically significantly associated with a reduced likelihood of late-stage diagnosis (adjusted OR (AOR)=0.85, 95% CI 0.80 to 0.91, p<0.01). However, screening was also associated with a higher likelihood of treatment delay (AOR=1.09, 95% CI 1.00 to 1.19, p=0.049). Taken together, the screening programme is associated with a slightly lower hazard of death (adjusted HR=0.94, 95% CI 0.89 to 0.99, p=0.01).
conclusionWhile Taiwan's nationwide oral cancer screening programme effectively reduced late-stage diagnoses and mortality, barriers to timely treatment access remain. Ensuring prompt diagnosis and treatment following screening may further enhance the survival benefits of the programme.
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