Evidence map›Paper›PMID 39622385›Full record

ArticleVirus research2024

Wild Brazilian yellow fever virus infection in Syrian hamsters (Mesocricetus auratus): Clinical and histopathological analyses.

Fernanda de Oliveira Bottino, Barbara Cristina Euzebio Pereira Dias de Oliveira, João Paulo Rodrigues Dos Santos, Mariana Barata Viana Tiradentes, Yuli Rodrigues Maia de Souza, Tainah Silva Galdino de Paula, Hyago da Silva Medeiros Elido, Isabele Barbieri Dos Santos, Ieda Pereira Ribeiro, Myrna Cristina Bonaldo and 2 more

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In one paragraph

Article in Virus research, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Fernanda de Oliveira BottinoLaboratory of Experimental Medicine and Health (Lames), Oswaldo Cruz Institute, Oswaldo Cruz Foundation, Rio de Janeiro, , Brazil; Laboratory of Professional Education in Laboratory Techniques in Health (Latec), Polytechnic School of Health Joaquim Venancio, Oswaldo Cruz Foundation, Rio de Janeiro, Brazil. Electronic address: fernanda_bottino4@hotmail.com.
Barbara Cristina Euzebio Pereira Dias de OliveiraLaboratory of Experimental Medicine and Health (Lames), Oswaldo Cruz Institute, Oswaldo Cruz Foundation, Rio de Janeiro, , Brazil.
João Paulo Rodrigues Dos SantosLaboratory of Experimental Medicine and Health (Lames), Oswaldo Cruz Institute, Oswaldo Cruz Foundation, Rio de Janeiro, , Brazil.
Mariana Barata Viana TiradentesLaboratory of Experimental Medicine and Health (Lames), Oswaldo Cruz Institute, Oswaldo Cruz Foundation, Rio de Janeiro, , Brazil.
Yuli Rodrigues Maia de SouzaLaboratory of Experimental Medicine and Health (Lames), Oswaldo Cruz Institute, Oswaldo Cruz Foundation, Rio de Janeiro, , Brazil.
Tainah Silva Galdino de PaulaLaboratory of Professional Education in Laboratory Techniques in Health (Latec), Polytechnic School of Health Joaquim Venancio, Oswaldo Cruz Foundation, Rio de Janeiro, Brazil.
Hyago da Silva Medeiros ElidoInstitute of Science and Technology of Biomodels, Oswaldo Cruz Foundation, Rio de Janeiro, Brazil.
Isabele Barbieri Dos SantosInstitute of Science and Technology of Biomodels, Oswaldo Cruz Foundation, Rio de Janeiro, Brazil.
Ieda Pereira RibeiroLaboratory of Experimental Medicine and Health (Lames), Oswaldo Cruz Institute, Oswaldo Cruz Foundation, Rio de Janeiro, , Brazil.
Myrna Cristina BonaldoLaboratory of Experimental Medicine and Health (Lames), Oswaldo Cruz Institute, Oswaldo Cruz Foundation, Rio de Janeiro, , Brazil.
Marcelo Pelajo MachadoLaboratory of Experimental Medicine and Health (Lames), Oswaldo Cruz Institute, Oswaldo Cruz Foundation, Rio de Janeiro, , Brazil; Brazilian National Institute on Neuroimmunomodulation, Oswaldo Cruz Institute, Oswaldo Cruz Foundation, Rio de Janeiro, Brazil.
Pedro Paulo de Abreu MansoLaboratory of Experimental Medicine and Health (Lames), Oswaldo Cruz Institute, Oswaldo Cruz Foundation, Rio de Janeiro, , Brazil.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The Yellow Fever virus (YFV) wild-type strains studied until now have little or no ability to evade the Syrian hamster interferon antiviral response. Thus, evaluating the susceptibility of this model to new YFV isolates is paramount to aid in the understanding of their viscerotropic phenotype. To this end, Syrian hamsters were inoculated intraperitoneally with two Brazilian wild-type YFV isolates originated from dying or dead howler monkeys obtained during outbreaks in the states of Rio Grande do Sul in 2008 (PR4408) and Rio de Janeiro in 2019 (RJ155). The results were compared with a YFV experimental vaccine strain (17DD

Indexed as

MesocricetusYellow FeverYellow fever virusAnimalsAntigens, ViralBrazilKidneyLiverMalePancreasRNA, ViralSpleenViremiaWeight LossAntigens, ViralRNA, ViralHamster modelNon-hamster-adapted strainsPR4408 strainYellow fever virus

Identifiers

PMID39622385
PMCPMC11667703

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LicenceCC BY-NC
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.