Evidence map›Paper›PMID 39622277›Full record

ArticleJournal of biophotonics2025

Shear Wave Optical Coherence Elastography and Structural Analysis of the Postnatal Mouse Cornea through Development.

Andrew L Lopez, Mohammad Dehshiri, Alexander W Schill, Salavat Aglyamov, Kirill Larin

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Journal of biophotonics, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Phantoms for use in optical coherence elastography.Journal of biomedical optics · 2026
    Review
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Andrew L LopezDepartment of Biomedical Engineering, University of Houston, Houston, Texas, USA.
Mohammad DehshiriDepartment of Biomedical Engineering, University of Houston, Houston, Texas, USA.
Alexander W SchillDepartment of Biomedical Engineering, University of Houston, Houston, Texas, USA.
Salavat AglyamovDepartment of Mechanical and Aerospace Engineering, University of Houston, Houston, Texas, USA.
Kirill LarinDepartment of Biomedical Engineering, University of Houston, Houston, Texas, USA.

Funding

Research Programming ModuleP30EY007551 · NEI · UNIVERSITY OF HOUSTON · PI Nimesh Bhikhu Patel · 1988 to 2026
$16.4M
Optical Coherence Elastography of the CorneaR01EY022362 · NEI · UNIVERSITY OF HOUSTON · PI Salavat R Aglyamov, Kirill V Larin · 2012 to 2026
$6.7M
Biomechanics of accommodationR01EY030063 · NEI · UNIVERSITY OF HOUSTON · PI LARIN, KIRILL V, MANNS, FABRICE · 2020 to 2024
$3.0M
No-Touch High Resolution Optical Coherence Elastography of the Cornea using a HeartbeatR01EY033978 · NEI · UNIVERSITY OF HOUSTON · PI Kirill V Larin · 2022 to 2026
$2.9M
NEI NIH HHS P30 EY007551NEI NIH HHS R01 EY022362NEI NIH HHS R01 EY030063NEI NIH HHS R01 EY033978NIH HHS R01EY022362NIH HHS R01EY030063NIH HHS R01EY033978
6 · The paper itself

Abstract

The cornea is a transparent lens at the forefront of the eye, serving as a structural barrier that protects the eye and provides the majority of the eye's refractive power. In this study, we utilized the postnatal mouse eye to characterize corneal structure and biomechanics. Between postnatal day (PN) 6 and PN24, we observed that elastic wave speeds are highest at PN6, gradually decrease through PN24, and then start to rise in adulthood (6 months). We found that corneal thickness is uncoupled from elastic wave speed and that the content and organization of the cornea primarily influence its mechanical properties. To the best of our knowledge, this work is the first detailed assessment of the postnatal mouse cornea's structure and biomechanics and warrants further investigation into the dynamic properties of the postnatal eye.

Indexed as

CorneaElasticity Imaging TechniquesTomography, Optical CoherenceAnimalsAnimals, NewbornBiomechanical PhenomenaElasticityMiceMice, Inbred C57BLbiomechanicscorneadevelopmentmouseoptical coherence elastographypostnatal

Identifiers

PMID39622277
PMCPMC12127497

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.