Evidence map›Paper›PMID 39622009›Full record

ArticleOrganic letters2024

Spiropyran as Building Block in Peptide Synthesis and Modulation of Photochromic Properties.

André Paschold, Niclas Starke, Sven Rothemund, Wolfgang H Binder

Abstract read
In one paragraph

Article in Organic letters, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

André PascholdMacromolecular Chemistry, Institute of Chemistry, Faculty of Natural Science II, Martin Luther University Halle Wittenberg, von-Danckelmann-Platz 4, 06120 Halle, Germany.
Niclas StarkeMacromolecular Chemistry, Institute of Chemistry, Faculty of Natural Science II, Martin Luther University Halle Wittenberg, von-Danckelmann-Platz 4, 06120 Halle, Germany.
Sven RothemundCore Unit Peptide-Technologies, University of Leipzig Medical Center, Liebigstraße 21, 04103 Leipzig, Germany.
Wolfgang H BinderMacromolecular Chemistry, Institute of Chemistry, Faculty of Natural Science II, Martin Luther University Halle Wittenberg, von-Danckelmann-Platz 4, 06120 Halle, Germany.ORCID 0000-0003-3834-5445

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Light-controlled triggering of materials requires efficient embedding of molecular photoswitches into larger molecules. We herein present the synthesis of two new building blocks for the synthesis of photoswitchable peptides, embedding spiropyranes as a central unit into peptide-backbones via a novel, yet unreported approach. The synthesis presented here allows us to embed spiropyranes directly into solid-phase peptide synthesis (SPPS), further describing the resulting photophysical properties of the as-prepared photoswitchable peptides.

Indexed as

BenzopyransIndolesNitro CompoundsPeptidesMolecular StructurePhotochemical ProcessesSolid-Phase Synthesis TechniquesBenzopyransIndolesNitro CompoundsPeptidesspiropyran

Identifiers

PMID39622009
PMCPMC11650765

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.