Evidence map›Paper›PMID 39621969›Full record

ArticleJournal of clinical oncology : official journal of the American Society of Clinical Oncology2025

Influence of Nucleophosmin (

Claudia Tregnago, Maddalena Benetton, Rhonda E Ries, Jack H Peplinski, Todd A Alonzo, Derek Stirewalt, Megan Othus, Nicolas Duployez, Edwin Sonneveld, Jonas Abrahamsson and 7 more

Abstract readMulticenter Study
PubMed Full text at PMC Publisher
In one paragraph

Article in Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Trial
  2. Article
  3. Article
  4. Using genomics to refine pediatric AML risk stratification.Hematology. American Society of Hematology. Education Program · 2025
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

17 authors.

Claudia TregnagoDepartment of Women's and Children's Health, Onco-hematology Lab and Clinic, University of Padova, Padova, Italy.ORCID 0000-0001-8122-0555
Maddalena BenettonDepartment of Women's and Children's Health, Onco-hematology Lab and Clinic, University of Padova, Padova, Italy.ORCID 0000-0003-3411-8878
Rhonda E RiesTranslational Sciences and Therapeutics, Fred Hutchinson Cancer Center, Seattle, WA.
Jack H PeplinskiTranslational Sciences and Therapeutics, Fred Hutchinson Cancer Center, Seattle, WA.ORCID 0000-0001-5097-0652
Todd A AlonzoUniversity of Southern California, Los Angeles, CA.
Derek StirewaltTranslational Sciences and Therapeutics, Fred Hutchinson Cancer Center, Seattle, WA.ORCID 0000-0003-4151-3171
Megan OthusSWOG Statistics and Data Management Center, Fred Hutchinson Cancer Center, Seattle, WA.ORCID 0000-0001-8176-6371
Nicolas DuployezLaboratory of Hematology, Lille University Hospital, Lille, France.ORCID 0000-0002-3927-1022
Edwin SonneveldPrincess Máxima Center for Pediatric Oncology, Utrecht, the Netherlands.
Jonas AbrahamssonInstitution for Clinical Sciences, Department of Pediatrics, Sahlgrenska Academy, University of Gothenburg, Gothenburg, Sweden.ORCID 0000-0002-9240-3522
Linda FogelstrandDepartment of Laboratory Medicine, Sahlgrenska Academy University of Gothenburg, Gothenburg, Sweden.ORCID 0000-0003-3698-8519
Nils von NeuhoffDepartment of Pediatric Hematology and Oncology, University Hospital Essen, Essen, Germany.
Henrik HasleDepartment of Pediatrics and Adolescent Medicine, Aarhus University Hospital, Aarhus, Denmark.ORCID 0000-0003-3976-9231
Dirk ReinhardtDepartment of Pediatric Hematology and Oncology, University Hospital Essen, Essen, Germany.ORCID 0000-0002-7027-4483
Soheil MeshinchiTranslational Sciences and Therapeutics, Fred Hutchinson Cancer Center, Seattle, WA.
Franco LocatelliDepartment of Pediatric Hematology and Oncology, IRCCS Ospedale Pediatrico Bambino Gesù, Catholic University of the Sacred Heart, Rome, Italy.ORCID 0000-0002-7976-3654
Martina PigazziDepartment of Women's and Children's Health, Onco-hematology Lab and Clinic, University of Padova, Padova, Italy.

Funding

NCTN BIQSFP ANBL1531 (NRT)U10CA180886 · NCI · PUBLIC HEALTH INSTITUTE · PI Douglas S. Hawkins · 2014 to 2026
$390.6M
COG SDMC - Statistics CoreU10CA180899 · NCI · UNIVERSITY OF SOUTHERN CALIFORNIA · PI TODD A ALONZO · 2014 to 2026
$132.8M
SWOG Statistics & Data Management Center complex - extension supplement for GY06U10CA180819 · NCI · FRED HUTCHINSON CANCER RESEARCH CENTER · PI MEGAN OTHUS · 2014 to 2026
$115.2M
NCI NIH HHS U10 CA180819NCI NIH HHS U10 CA180886NCI NIH HHS U10 CA180899
6 · The paper itself

Abstract

purposeSeveral genomic subsets of MATERIALS AND

methodsOf more than 4,000 patients enrolled in multiple pediatric cooperative (AIEOP, BFM, ELAM02, NOPHO, DCOG, and COG trials), or adult (SWOG) trials, 348 pediatric and 75 adult AML patients with known

resultsEvaluation of clinical outcome on the basis of

conclusionThe evaluation of specific

Indexed as

Leukemia, Myeloid, AcuteNuclear ProteinsAdolescentAdultAgedChildChild, PreschoolFemaleGenotypeHumansMaleMiddle AgedMutationNucleophosminPrognosisYoung AdultNPM1 protein, humanNuclear ProteinsNucleophosmin

Identifiers

PMID39621969
PMCPMC12363388

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.