Evidence map›Paper›PMID 39621611›Full record

SynthesisPloS one2024

A meta-analysis of technology-based interventions on treatment adherence and treatment success among TBC patients.

Mega Hasanul Huda, Muhamad Fauzi Rahman, Yusuf Zalaya, Muhammad Amirul Mukminin, Telly Purnamasari, Harimat Hendarwan, Amir Su'udi, Armedy Ronny Hasugian, Yuyun Yuniar, Rini Sasanti Handayani and 5 more

Abstract readMeta-AnalysisSystematic Review
In one paragraph

Synthesis in PloS one, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Article
  3. Article
  4. Article
  5. Article
  6. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors.

Mega Hasanul HudaFaculty of Nursing, University of Indonesia, Depok, West Java, Indonesia.ORCID 0000-0002-8381-7774
Muhamad Fauzi RahmanCollege of Public Health, Taipei Medical University, New Taipei City, Taiwan.ORCID 0000-0001-5445-8410
Yusuf ZalayaFaculty of Public Health, University of Indonesia, Depok, West Java, Indonesia.
Muhammad Amirul MukmininSchool of Nursing, College of Nursing, Taipei Medical University, New Taipei City, Taiwan.ORCID 0000-0001-5246-1122
Telly PurnamasariResearch Center for Pre-Clinical and Clinical Medicine, National Research and Innovation Agency, Cibinong Science Center, Cibinong, West Java, Indonesia.
Harimat HendarwanResearch Center for Pre-Clinical and Clinical Medicine, National Research and Innovation Agency, Cibinong Science Center, Cibinong, West Java, Indonesia.ORCID 0000-0002-0248-9271
Amir Su'udiResearch Center for Pre-Clinical and Clinical Medicine, National Research and Innovation Agency, Cibinong Science Center, Cibinong, West Java, Indonesia.ORCID 0000-0001-9399-6991
Armedy Ronny HasugianResearch Center for Pre-Clinical and Clinical Medicine, National Research and Innovation Agency, Cibinong Science Center, Cibinong, West Java, Indonesia.ORCID 0000-0002-3255-9218
Yuyun YuniarResearch Center for Pre-Clinical and Clinical Medicine, National Research and Innovation Agency, Cibinong Science Center, Cibinong, West Java, Indonesia.ORCID 0000-0003-4501-4142
Rini Sasanti HandayaniResearch Center for Pre-Clinical and Clinical Medicine, National Research and Innovation Agency, Cibinong Science Center, Cibinong, West Java, Indonesia.
Rudi Hendro PutrantoResearch Center for Pre-Clinical and Clinical Medicine, National Research and Innovation Agency, Cibinong Science Center, Cibinong, West Java, Indonesia.ORCID 0000-0003-2015-320X
Aris YuliantoResearch Center for Pre-Clinical and Clinical Medicine, National Research and Innovation Agency, Cibinong Science Center, Cibinong, West Java, Indonesia.ORCID 0000-0001-6493-410X
Anton SuryatmaResearch Center for Pre-Clinical and Clinical Medicine, National Research and Innovation Agency, Cibinong Science Center, Cibinong, West Java, Indonesia.ORCID 0000-0001-6313-8611
Mieska DespitasariResearch Center for Pre-Clinical and Clinical Medicine, National Research and Innovation Agency, Cibinong Science Center, Cibinong, West Java, Indonesia.ORCID 0000-0002-3553-7794
Riswal Nafi SiregarResearch Center for Pre-Clinical and Clinical Medicine, National Research and Innovation Agency, Cibinong Science Center, Cibinong, West Java, Indonesia.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Various technology-based interventions have been designed to improve medication adherence and treatment success. However, research on the most effective mode to address this issue is still limited. Our study evaluated the effectiveness of technology-based interventions in improving treatment adherence, completion, and treatment success among tuberculosis (TBC) patients. We conducted a meta-analysis of randomized controlled trials by searching articles from six databases including PubMed, Science Direct, Cochrane, Jstor, Embase, and Scopus from 2018 to April 2023. Two independent reviewers assessed the study quality using the Cochrane Risk of Bias 2.0 tool. We analysed the data using a random-effects model. We also conducted publication bias and sensitivity analysis. In total, 13 studies were identified and 4,794 participants were included in the meta-analysis. The results indicated that technology-based interventions were effective in improving treatment adherence, completion, and success (Odds Ratio (OR): 2.57, 95% Confident Interval (CI): 1.01-6.50, I2 = 86.6%; OR: 1.77, 95% CI: 0.95-3.28, I2: 82.3%; OR: 1.61, 95% CI: 0.85-3.06, I2: 84%, respectively). We examined the possibility of publication bias in the published studies included in this systematic review. However, no evidence of publication bias was found. From the sensitivity analysis by removing one study randomly, we found that our results are robust. Based on the results, we can conclude that technology-based interventions like MERM, text-based messages, video conferencing, and VOT are effective in increasing treatment adherence and completion in tuberculosis management. Therefore, technology shows immense potential in enhancing patient outcomes.

Indexed as

Medication AdherenceTuberculosisAntitubercular AgentsHumansRandomized Controlled Trials as TopicTelemedicineText MessagingTreatment OutcomeAntitubercular Agents

Identifiers

PMID39621611
PMCPMC11611106

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.