Evidence map›Paper›PMID 39621176›Full record

ArticleInternational journal of clinical oncology2025

Effects of aging on complications following robot-assisted radical prostatectomy.

Shigeki Koterazawa, Masashi Kubota, Takayuki Sumiyoshi, Ryoichi Saito, Naoto Takaoka, Yuto Hattori, Yosuke Shimizu, Toru Kanno, Takeshi Soda, Yoshiyuki Okada and 9 more

Abstract read
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Article in International journal of clinical oncology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

19 authors.

Shigeki KoterazawaDepartment of Urology, Kyoto University School of Medicine, 54 Shougoinkawahara-Cho, Sakyo-Ku, Kyoto, 606-8507, Japan.
Masashi KubotaDepartment of Urology, Kyoto University School of Medicine, 54 Shougoinkawahara-Cho, Sakyo-Ku, Kyoto, 606-8507, Japan.
Takayuki SumiyoshiDepartment of Urology, Kyoto University School of Medicine, 54 Shougoinkawahara-Cho, Sakyo-Ku, Kyoto, 606-8507, Japan.
Ryoichi SaitoDepartment of Urology, Kyoto University School of Medicine, 54 Shougoinkawahara-Cho, Sakyo-Ku, Kyoto, 606-8507, Japan.
Naoto TakaokaDepartment of Urology, Tenri Hospital, Nara, Japan.
Yuto HattoriDepartment of Urology, Kobe City Medical Center General Hospital, Hyogo, Japan.
Yosuke ShimizuDepartment of Urology, Kobe City Nishi-Kobe Medical Center, Hyogo, Japan.
Toru KannoDepartment of Urology, National Hospital Organization Kyoto Medical Center, Kyoto, Japan.
Takeshi SodaDepartment of Urology, Tazuke Kofukai, Medical Research Institute, Kitano Hospital, Osaka, Japan.
Yoshiyuki OkadaDepartment of Urology, Kyoto-Katsura Hospital, Kyoto, Japan.
Kazunari TsuchihashiDepartment of Urology, Japanese Red Cross Otsu Hospital, Shiga, Japan.
Yuya SekineDepartment of Urology, Akita University Graduate School of Medicine, Akita, Japan.
Hiromitsu NegoroDepartment of Urology, University of Tsukuba, Ibaraki, Japan.
Ryoma KurahashiDepartment of Urology, Faculty of Life Sciences, Kumamoto University, Kumamoto, Japan.
Kimihiro ShimataniDepartment of Urology, Hyogo Medical University, Hyogo, Japan.
Atsuro SawadaDepartment of Urology, Miyazaki University, Miyazaki, Japan.
Shusuke AkamatsuDepartment of Urology, Nagoya University, Aichi, Japan.
Takayuki GotoDepartment of Urology, Kyoto University School of Medicine, 54 Shougoinkawahara-Cho, Sakyo-Ku, Kyoto, 606-8507, Japan. goto@kuhp.kyoto-u.ac.jp.ORCID http://orcid.org/0000-0001-6537-3068
Takashi KobayashiDepartment of Urology, Kyoto University School of Medicine, 54 Shougoinkawahara-Cho, Sakyo-Ku, Kyoto, 606-8507, Japan. selecao@kuhp.kyoto-u.ac.jp.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundFor prostate cancer (PCa) in the elderly, including patients ≥ 80 years, the safety of robot-assisted radical prostatectomy (RARP) is controversial. We aimed to evaluate the effect of aging on the postoperative complication rates after RARP.

methodsThis cohort study used a database of patients who had undergone RARP at 25 different institutes. We divided the cohort into four age groups (< 70, 70-74, 75-79, and ≥ 80 years). The complication rates after RARP in the 70-74, 75-79, and ≥ 80 year group were compared using the < 70 year group serving as the control group by applying the inverse probability of treatment weighting (IPTW)-adjusted regression analysis.

resultsA total of 8055 patients were evaluated. The postoperative complication rates were 8.8%, 9.7%, 9.6%, and 10.0% in the < 70, 71-74, 75-79, and ≥ 80 age groups, respectively. In IPTW-adjusted analyses, the risk of overall complications (< 70 vs. 70-74 year group: OR = 1.09 [95% CI 0.92-1.29]; < 70 vs. 75-79 year group: OR = 1.09 [95% CI 0.88-1.37], and < 70 vs. ≥ 80 year group: OR = 2.21 [95% CI 0.92-5.32]) did not change with increasing age. There was no significant increase in risk for any complication category, such as bowel dysfunction, symptomatic lymphocele, or bacterial infection, between the < 70 and ≥ 80 age groups.

conclusionOur findings showed that, in appropriately selected patients, the risk of complications after RARP did not increase with age, even at 75 or 80 years.

Indexed as

AgingPostoperative ComplicationsProstatectomyProstatic NeoplasmsRobotic Surgical ProceduresAgedAged, 80 and overAge FactorsHumansMaleMiddle AgedRisk FactorsAgingComplicationContinenceInverse probability of treatment weightingRobotic-assisted radical prostatectomy

Identifiers

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.