ArticleArchives of orthopaedic and trauma surgery2024
Thrombotic events in patients underwent simultaneous bilateral total knee arthroplasty with modern perioperative blood management strategy.
Article in Archives of orthopaedic and trauma surgery, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
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Who cites it
1 citing paper in PubMed.
- Management of Venous Thromboembolism After Hip and Knee Arthroplasty.Journal of orthopaedics and sports medicine · 2025Article
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Authors and funding
5 authors.
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No grant is acknowledged in the PubMed record.
Abstract
backgroundThrombotic events, the leading cause of death after total knee arthroplasty (TKA), occurred more frequently in simultaneous bilateral TKA than unilateral TKA under conventional perioperative management. The aim of the study was to determine whether the simultaneous bilateral TKA using contemporary blood management strategies would be associated with higher risk of thrombotic events than unilateral TKA.
methodThis propensity score-matched cohort study included 1,069 patients, with 324 undergoing simultaneous bilateral TKA and 745 undergoing unilateral TKA. All TKAs were performed without use of a tourniquet and with use of intravenous tranexamic acid administration. For patients receiving chronic antithrombotic therapy, the antithrombotic medications were continued during the perioperative period, including on the day of the operation. The primary outcome was the thrombotic events up to 1 year after TKA.
resultsThe propensity score-matched cohort consisted of 324 matched pairs of patients. There was no significant difference between simultaneous bilateral and unilateral TKA groups in the occurrence of the thrombotic events (25 of 324 [7.7%] versus 19 of 324 [5.9%] patients, p = 0.44). Additionally, no significant differences were found in the occurrence of the bleeding events (1 of 324 [0.3%] versus 1 of 324 [0.3%] patients, p > 0.99) and death within the postoperative 1 year (1 of 324 [0.3%] versus 3 of 324 [0.9%] patients, p = 0.62).
conclusionThe rate of thrombotic events after simultaneous bilateral TKA with contemporary perioperative blood management strategies did not significantly differ from that after unilateral TKA.
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