Evidence map›Paper›PMID 39620998›Full record

ArticleAnnals of Indian Academy of Neurology2025

Progressive Supranuclear Palsy in India: Past, Present, and Future.

Srinivas Raju, Kuldeep Shetty, Lulup Sahoo, Vijayashankar Paramanandam, Jay M Iyer, Suvorit Bowmick, Soaham Desai, Deepika Joshi, Niraj Kumar, Sahil Mehta and 14 more

Abstract read
In one paragraph

Article in Annals of Indian Academy of Neurology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Progressive Supranuclear Palsy-A Global Review.Movement disorders clinical practice · 2026
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

24 authors.

Srinivas RajuDepartment of Neurology, Manipal Hospital, Hebbal, Bengaluru, Karnataka, India.
Kuldeep ShettyDepartment of Neurology, Mazumdar Shaw Medical Center, Narayana Health City, Bengaluru, Karnataka, India.
Lulup SahooDepartment of Neurology, Institute of Medical Sciences and SUM Hospital, Bhubaneswar, Odisha, India.
Vijayashankar ParamanandamDepartment of Neurology, Apollo Hospitals, Greams Road, Chennai, Tamil Nadu, India.
Jay M IyerDepartments of Molecular and Cellular Biology and Statistics, Harvard University, Cambridge MA, USA.
Suvorit BowmickDepartment of Neurology, Vadodara Institute of Neurological Sciences, Vadodara, Gujarat, India.
Soaham DesaiDepartment of Neurology, Shree Krishna Hospital Pramukhswami Medical College Bhaikaka University, Karamsad Anand, Gujarat, India.
Deepika JoshiDepartment of Neurology, Institute of Medical Sciences, Banaras Hindu University, Varanasi, Uttar Pradesh, India.
Niraj KumarDepartment of Neurology, All India Institute of Medical Sciences, Bibinagar, Telangana, India.
Sahil MehtaDepartment of Neurology, Post Graduate Institute of Medical Education and Research, Chandigarh, India.
Rukmini Mridula KandadaiDepartment of Neurology, Citi Neuro Center, Hyderabad, Telangana, India.
Pettarusp WadiaMovement Disorder Clinic, Department of Neurology, Jaslok Hospital and Research Centre, Mumbai, Maharashtra, India.
Atanu BiswasDepartment of Neurology, Bangur Institute of Neurosciences and Institute of Post Graduate Medical Education and Research, Kolkata, West Bengal, India.
Divyani GargDepartment of Neurology, All India Institute of Medical Sciences, New Delhi, India.
Pankaj AgarwalGleneagles Hospital, Mumbai and King Edward Memorial Hospital, Mumbai, Maharashtra, India.
Syam KrishnanDepartment of Neurology, Sree Chitra Tirunal Institute for Medical Sciences and Technology, Thiruvananthapuram, Kerala, India.
Jacky GangulyDepartment of Neurology, Institute of Neurosciences Kolkata, Kolkata, West Bengal, India.
Heli ShahDepartment of Neurology, Jivraj Mehta Hospital, Ahmedabad, Gujarat, India.
Mitesh ChandaranaHealth 1 Super Specialty Hospitals, Ahmedabad, Gujarat, India.
Hrishikesh KumarDepartment of Neurology, Institute of Neurosciences Kolkata, Kolkata, West Bengal, India.
Rupam BorgohainDepartment of Neurology, Citi Neuro Center, Hyderabad, Telangana, India.
V L RamprasadDepartment of Genetics, MedGenome Labs Pvt Ltd, Bengaluru, Karnataka, India.
Prashanth Lingappa KukkleDepartment of Movement Disorders, Parkinson's Disease and Movement Disorders Clinic, Bengaluru, Karnataka, India.
PRAI Consortium

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Progressive supranuclear palsy (PSP) has emerged as a key area of interest among researchers worldwide, including those in India, who have actively studied the disorder over the past several decades. This review meticulously explores the extensive range of Indian research on PSP up to the present and offers insights into both current initiatives and potential future directions for managing PSP within the region. Historical research contributions have spanned 80 publications from 1974 to 2023, encompassing diverse themes from clinical phenotyping and historical analysis to isolated investigative studies and therapeutic trials. Traditionally, these studies have been conducted in single centers or specific departments, involving a broad range of recruitment numbers. The most frequently encountered phenotype among these studies is PSP-Richardson's syndrome, with patients typically presenting at an average age of 64 years, alongside various other subtypes. Recently, there has been a significant shift toward more collaborative research models, moving from isolated, center-based studies to expansive, multicentric, and pan India projects. A prime example of this new approach is the PAn India Registry for PSP (PAIR-PSP) project, which represents a comprehensive effort to uniformly examine the demographic, clinical, and genetic facets of PSP across India. Looking ahead, there is a critical need for focused research on unraveling genetic insights, identifying risk factors, and developing effective treatment interventions and preventive models. Given its vast population, India's role in advancing our understanding of PSP and other tauopathies could be pivotal, and this work reflects the work on PSP in India till now.

Identifiers

PMID39620998
PMCPMC11892962

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.