Evidence map›Paper›PMID 39620568›Full record

ArticleHip & pelvis2024

Biological Agent and Total Hip Arthroplasty in Rheumatoid Arthritis.

Yuya Takakubo, Kan Sasaki, Juji Ito, Hiroharu Oki, Masaji Ishii, Michiaki Takagi

Abstract read
In one paragraph

Article in Hip & pelvis, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Yuya TakakuboDepartment of Orthopaedic Surgery, Yamagata University Faculty of Medicine, Yamagata, Japan.ORCID https://orcid.org/0000-0003-3535-8419
Kan SasakiDepartment of Orthopaedic Surgery, Yamagata Saisei Hospital, Yamagata, Japan.ORCID https://orcid.org/0009-0000-8015-6379
Juji ItoDepartment of Orthopaedic Surgery, Yamagata University Faculty of Medicine, Yamagata, Japan.ORCID https://orcid.org/0000-0002-3410-2940
Hiroharu OkiDepartment of Orthopaedic Surgery, Yamagata Saisei Hospital, Yamagata, Japan.ORCID https://orcid.org/0009-0008-4983-239X
Masaji IshiiDepartment of Orthopaedic Surgery, Yamagata Saisei Hospital, Yamagata, Japan.ORCID https://orcid.org/0009-0005-7332-1897
Michiaki TakagiDepartment of Orthopaedic Surgery, Yamagata University Faculty of Medicine, Yamagata, Japan.ORCID https://orcid.org/0000-0002-3052-787X

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Purpose: Therapies for treatment of rheumatoid arthritis (RA) have shown significant improvement since the introduction of biological agents (BIO) in 2003 and Janus kinase inhibitors (JAKi) in 2013 in Japan. The rate of orthopedic surgery, including total hip arthroplasties (THA), may reflect trends in disease severity, management, and health outcomes. Materials and Methods: An analysis of data on THAs performed at our institutes for treatment of RA with BIO or non-BIO therapy from 2004 to 2021 was conducted. Results: A total of 40,328 orthopedic surgeries, including 5,938 primary THAs and 204 RA-THAs, were performed between 2004 and 2021. An increase in the annual rate of THA performed for patients undergoing orthopedic surgery was observed. The rates of THA decreased annually for patients with RA when compared to the total number of orthopedic surgeries and primary THAs performed. Conclusion: The number of THAs performed for patients with RA may show an annual decrease resulting from early and aggressive drug therapy for management of RA in the era of BIO and JAKi. However, patients with RA undergoing THA have several unmet needs, including secondary osteoarthritis, dislocation, periprosthetic joint infection, and periprosthetic fracture with osteoporosis.

Indexed as

Biological agentsJanus kinase inhibitorsRheumatoid arthritisTotal hip arthroplasties

Identifiers

PMID39620568
PMCPMC11638749

What OpenQuestion holds

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LicenceCC BY-NC
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.