Evidence map›Paper›PMID 39620392›Full record

ArticleChemistry, an Asian journal2025

A New Bis-Urea Based Cage Receptor for Anions: Synthesis, Solid State Structures and Binding Studies.

Daniele Paderni, Mauro Formica, Eleonora Macedi, Luca Giorgi, Patrizia Rossi, Michele Retini, Nicola De Cata, Giovanni Zappia, Giovanni Piersanti, Vieri Fusi

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Chemistry, an Asian journal, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Daniele PaderniDepartment of Pure and Applied Sciences, University of Urbino Carlo Bo, via Ca' le Suore 2-4, 61029, Urbino, Italy.ORCID https://orcid.org/0000-0003-4598-5117
Mauro FormicaDepartment of Pure and Applied Sciences, University of Urbino Carlo Bo, via Ca' le Suore 2-4, 61029, Urbino, Italy.ORCID https://orcid.org/0000-0002-2087-4624
Eleonora MacediDepartment of Pure and Applied Sciences, University of Urbino Carlo Bo, via Ca' le Suore 2-4, 61029, Urbino, Italy.ORCID https://orcid.org/0000-0003-0251-901X
Luca GiorgiDepartment of Pure and Applied Sciences, University of Urbino Carlo Bo, via Ca' le Suore 2-4, 61029, Urbino, Italy.ORCID https://orcid.org/0000-0001-5734-2835
Patrizia RossiDepartment of Industrial Engineering, University of Firenze, via Santa Marta 3, 50139, Firenze, Italy.ORCID https://orcid.org/0000-0002-6316-338X
Michele RetiniDepartment of Biomolecular Sciences, University of Urbino Carlo Bo, via Ca' le Suore 2-4, 61029, Urbino, Italy.ORCID https://orcid.org/0000-0003-0218-8505
Nicola De CataDepartment of Biomolecular Sciences, University of Urbino Carlo Bo, via Ca' le Suore 2-4, 61029, Urbino, Italy.
Giovanni ZappiaDipartimento di Promozione delle Scienze Umane e della Qualità della Vita, University San Raffaele, via di Val Cannuta, 247, Rome, Italy.
Giovanni PiersantiDepartment of Biomolecular Sciences, University of Urbino Carlo Bo, via Ca' le Suore 2-4, 61029, Urbino, Italy.ORCID https://orcid.org/0000-0003-0418-7143
Vieri FusiDepartment of Pure and Applied Sciences, University of Urbino Carlo Bo, via Ca' le Suore 2-4, 61029, Urbino, Italy.ORCID https://orcid.org/0000-0002-7627-8637

Funding

DISPEA ASSEGNAZIONE SICUREZZA ALIMENTARE
6 · The paper itself

Abstract

The synthesis and characterization of a novel bis-urea-based cage receptor for anions (3S,15S)-3,15,20,25-tetramethyl-1,4,6,12,14,17,20,25-octaazatricyclo[15.5.5.17.11]octacosa-7(28),10-diene-2,5,13,16-tetraone (L) is reported. L is a macro-bicyclic ligand built on the 1,7-dimethyl-1,4,7,10-tetraazacyclododecane scaffold to obtain a cage topology in which two ureido moieties have been inserted as binding sites for anions. L can interact with anion guests (G) via H-bonding; in particular, it binds both spherical (Cl

Indexed as

Anions coordinationAza-macrocycleCage compoundsNorfloxacin Urea

Identifiers

PMID39620392
PMCPMC11741156

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.