Evidence map›Paper›PMID 39620060›Full record

ArticleBioMed research international2024

Biodegradation Study of Biomaterials Composed of Acrylated Epoxidized Soybean Oil: An In Vitro Study.

Diego Sibilia, Martina Amendolea, Roberta Sangiovanni, Mario Bragaglia, Fabrizio Nicoletti, Pierfrancesco Filetici, Antonio D'Addona, Francesca Nanni, Leonardo Dassatti, Giuseppina Nocca

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Article in BioMed research international, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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0citing papers in PubMed
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1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Diego SibiliaDipartimento di Scienze della Vita e Sanità Pubblica, Università Cattolica del Sacro Cuore, Largo F. Vito, 1 00168, Rome, Italy.ORCID https://orcid.org/0009-0001-6802-9059
Martina AmendoleaHead and Neck Department, School of Dentistry, Fondazione Policlinico Universitario A. Gemelli-IRCCS, Università Cattolica del Sacro Cuore, Largo A. Gemelli 8, Rome 00168, Italy.
Roberta SangiovanniHead and Neck Department, School of Dentistry, Fondazione Policlinico Universitario A. Gemelli-IRCCS, Università Cattolica del Sacro Cuore, Largo A. Gemelli 8, Rome 00168, Italy.
Mario BragagliaDepartment of Enterprise Engineering, University of Rome "Tor Vergata", Via del Politecnico 1 00133, Rome, Italy.ORCID https://orcid.org/0000-0002-5921-0884
Fabrizio NicolettiHead and Neck Department, School of Dentistry, Fondazione Policlinico Universitario A. Gemelli-IRCCS, Università Cattolica del Sacro Cuore, Largo A. Gemelli 8, Rome 00168, Italy.
Pierfrancesco FileticiHead and Neck Department, School of Dentistry, Fondazione Policlinico Universitario A. Gemelli-IRCCS, Università Cattolica del Sacro Cuore, Largo A. Gemelli 8, Rome 00168, Italy.
Antonio D'AddonaHead and Neck Department, School of Dentistry, Fondazione Policlinico Universitario A. Gemelli-IRCCS, Università Cattolica del Sacro Cuore, Largo A. Gemelli 8, Rome 00168, Italy.
Francesca NanniDepartment of Enterprise Engineering, University of Rome "Tor Vergata", Via del Politecnico 1 00133, Rome, Italy.
Leonardo DassattiHead and Neck Department, School of Dentistry, Fondazione Policlinico Universitario A. Gemelli-IRCCS, Università Cattolica del Sacro Cuore, Largo A. Gemelli 8, Rome 00168, Italy.
Giuseppina NoccaFondazione Policlinico Universitario A. Gemelli, IRCCS, Largo A. Gemelli 8 00168, Rome, Italy.ORCID https://orcid.org/0000-0002-2799-4557

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

In the field of regenerative medicine, acrylated epoxidized vegetable oils are emerging as a promising avenue of exploration. The aim of this study is to evaluate the degradability of two formulations of acrylated epoxidized soybean oil (AESO): pure AESO and AESO diluted with soybean oil (SO) for potential bioprintability applications. The comprehensive investigation of these two polymeric formulations included optimization of polymerization conditions, confirmation of cytocompatibility, and, most importantly, the study of their degradability. The results reveal that AESO, used as a biomaterial for biomedical applications, undergoes a distinctive degradation process, combining both enzymatic and oxidative degradation (AESO/SO samples lose 29.45% of their weight after 60 days). This phenomenon is the result of a complex interplay of factors, including the chemical composition and physical characteristics of the polymer, the unique tissue environment in which it is implanted, and the duration of implantation.

Indexed as

Biocompatible MaterialsMaterials TestingSoybean OilAnimalsHumansMicePolymersBiocompatible Materialsepoxidized soybean oilPolymersSoybean Oilacrylated oilsbiodegradationcytotoxicityphotopolymerizationregenerative medicine

Identifiers

PMID39620060
PMCPMC11608301

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.