Evidence map›Paper›PMID 39619708›Full record

ArticleThe Saudi dental journal2024

Mutagenicity and DNA damage assessment of locally produced nano-hydroxyapatite-silica-glass ionomer cement on human periodontal ligament fibroblasts using Ames and Comet assays.

Fayez Hussain Niazi, Norhayati Luddin, Abdurahman Niazy, Suharni Mohamad, Masitah Hayati Harun, Mohammed Noushad, Kannan Thirumulu Ponnuraj

Abstract read
In one paragraph

Article in The Saudi dental journal, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Fayez Hussain NiaziSchool of Dental Sciences, Universiti Sains Malaysia, 16150 Kubang Kerian, Kelantan, Malaysia.
Norhayati LuddinSchool of Dental Sciences, Universiti Sains Malaysia, 16150 Kubang Kerian, Kelantan, Malaysia.
Abdurahman NiazyDepartment of Oral Medicine and Diagnostic Sciences, College of Dentistry, King Saud University, Riyadh 11495, Saudi Arabia.
Suharni MohamadSchool of Dental Sciences, Universiti Sains Malaysia, 16150 Kubang Kerian, Kelantan, Malaysia.
Masitah Hayati HarunSchool of Dental Sciences, Universiti Sains Malaysia, 16150 Kubang Kerian, Kelantan, Malaysia.
Mohammed NoushadDepartment of Restorative and Prosthetic Dentistry, College of Dentistry, Dar Al Uloom University, Riyadh 13314, Saudi Arabia.
Kannan Thirumulu PonnurajSchool of Dental Sciences, Universiti Sains Malaysia, 16150 Kubang Kerian, Kelantan, Malaysia.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Aim: This research assessed the mutagenicity and DNA damage of a novel type of nano-hydroxyapatite-silica glass ionomer cement (nano-HA-SiO Methods: Cell viability was tested on human periodontal ligament fibroblasts (HPLFs) using 3.125 mg/ml, 6.25, 12.5, 25, 50, 100 and 200 mg/ml, on both types of GICs employing MTT assay. For the Comet assay, HPLFs were treated with IC Results: The highest cell viability (159.4 %) for nano-HA-SiO Conclusions: It can be concluded that nano-HA-SiO

Indexed as

Cell viabilityDNA damageGenotoxicityHuman periodontal ligament fibroblastMutagenicityNano-hydroxyapatite-silica-glass ionomer cement

Identifiers

PMID39619708
PMCPMC11605718

What OpenQuestion holds

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LicenceCC BY-NC-ND
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.