Evidence map›Paper›PMID 39619358›Full record

ArticleJournal of geriatric cardiology : JGC2024

Routine invasive strategy and frailty burden in non-ST-segment elevation acute myocardial infarction.

Albert Ariza-Solé, Juan Andrés Bermeo, Francesc Formiga, Héctor Bueno, Gemma Miñana, Oriol Alegre, David Martí, Manuel Martínez-Sellés, Laura Domínguez-Pérez, Pablo Díez-Villanueva and 15 more

Abstract read
In one paragraph

Article in Journal of geriatric cardiology : JGC, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

25 authors.

Albert Ariza-SoléCardiology Department, Hospital Universitari de Bellvitge, L'Hospitalet de Llobregat, Barcelona, Spain.
Juan Andrés BermeoCardiology Department, Hospital Universitari de Bellvitge, L'Hospitalet de Llobregat, Barcelona, Spain.
Francesc FormigaInternal Medicine Department, Hospital Universitari de Bellvitge, L'Hospitalet de Llobregat, Barcelona, Spain.
Héctor BuenoCentro Nacional de Investigaciones Cardiovasculares (CNIC), Madrid, Spain; Cardiology Department, Hospital 12 de Octubre, and Instituto de Investigación Sanitaria Hospital 12 de Octubre (imas12), Madrid, CIBERCV, Madrid, Spain; Universidad Complutense, Madrid, Spain.
Gemma MiñanaCardiology Department, Hospital Clínico Universitario de Valencia, INCLIVA, Universidad de Valencia, CIBERCV, Valencia, Spain.
Oriol AlegreCardiology Department, Hospital Universitari de Bellvitge, L'Hospitalet de Llobregat, Barcelona, Spain.
David MartíCardiology Department, Hospital Central de la Defensa, Madrid, Spain.
Manuel Martínez-SellésCardiology Department, Hospital Universitario Gregorio Marañón, CIBERCV, Universidad Complutense, Universidad Europea, Madrid, Spain.
Laura Domínguez-PérezCentro Nacional de Investigaciones Cardiovasculares (CNIC), Madrid, Spain; Cardiology Department, Hospital 12 de Octubre, and Instituto de Investigación Sanitaria Hospital 12 de Octubre (imas12), Madrid, CIBERCV, Madrid, Spain; Universidad Complutense, Madrid, Spain.
Pablo Díez-VillanuevaCardiology Department, Hospital Universitario La Princesa, IIS-IP, CIBERCV, Madrid, Spain.
José A BarrabésCardiology Department, Hospital Universitari Vall d'Hebron, CIBERCV, Barcelona, Spain.
Francisco MarínCardiology Department, Hospital Virgen de la Arrixaca, CIBERCV, El Palmar, Murcia, Spain.
Adolfo VillaCardiology Department, Hospital Universitario del Sureste, Arganda del Rey, Madrid, Spain.
Marcelo SanmartínCardiology Department, Hospital Ramon y Cajal, CIBERCV, Madrid, Spain.
Cinta LlibreCardiology Department, Hospital Germans Trias i Pujol, CIBERCV, Badalona, Barcelona, Spain.
Alessandro SionísCardiology Department, Hospital Sant Pau, CIBERCV, Barcelona, Spain.
Antoni CarolCardiology Department, Hospital Moisés Broggi, Sant Joan Despí, Barcelona, Spain.
Sergio García-BlasCardiology Department, Hospital Clínico Universitario de Valencia, INCLIVA, Universidad de Valencia, CIBERCV, Valencia, Spain.
María José Morales GallardoCardiology Department, Hospital Central de la Defensa, Madrid, Spain.
Jaime ElízagaCardiology Department, Hospital Universitario Gregorio Marañón, CIBERCV, Universidad Complutense, Universidad Europea, Madrid, Spain.
Iván Gómez-BlázquezCentro Nacional de Investigaciones Cardiovasculares (CNIC), Madrid, Spain; Cardiology Department, Hospital 12 de Octubre, and Instituto de Investigación Sanitaria Hospital 12 de Octubre (imas12), Madrid, CIBERCV, Madrid, Spain; Universidad Complutense, Madrid, Spain.
Fernando AlfonsoCardiology Department, Hospital Universitario La Princesa, IIS-IP, CIBERCV, Madrid, Spain.
Bruno García Del BlancoCardiology Department, Hospital Universitari Vall d'Hebron, CIBERCV, Barcelona, Spain.
Julio NúñezCardiology Department, Hospital Clínico Universitario de Valencia, INCLIVA, Universidad de Valencia, CIBERCV, Valencia, Spain.
Juan SanchisCardiology Department, Hospital Clínico Universitario de Valencia, INCLIVA, Universidad de Valencia, CIBERCV, Valencia, Spain.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Objective: To assess the prognostic impact of a routine invasive strategy according to the frailty burden in patients with non-ST-segment elevation myocardial infarction (NSTEMI) from the MOSCA-FRAIL clinical trial. Methods: The MOSCA-FRAIL trial randomized 167 frail patients, defined by a Clinical Frailty Scale (CFS) ≥ 4, with NSTEMI to an invasive or conservative strategy. The primary endpoint was the number of days alive and out of hospital (DAOH) one year after discharge. For this subanalysis, we compared the impact of an invasive strategy on the outcomes between vulnerable (CFS = 4, Results: Compared to vulnerable patients, frail patients presented lower values of DAOH (289.8 Conclusions: Adult patients with frailty and NSTEMI showed different prognosis according to the degree of frailty. A routine invasive strategy does not improve outcomes and might be harmful to the frailest patients.

Identifiers

PMID39619358
PMCPMC11605503

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.