Evidence map›Paper›PMID 39619350›Full record

ArticlePsychiatry and clinical psychopharmacology2021

The Assessment of Cognitive Dysfunction in Major Depressive Disorder: A 16-Week Prospective Case-Control Study.

Fikret Poyraz Çökmüş, Hüseyin Murat Özkan, Didem Sücüllüoğlu-Dikci, Kadir Aşçibaşi, Deniz Alçi, Neslihan Altunsoy, Erkan Kuru, Serra Yüzeren, Ömer Aydemir

Abstract read
In one paragraph

Article in Psychiatry and clinical psychopharmacology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Fikret Poyraz ÇökmüşPsychiatry Clinic, Manisa Mental Health and Diseases Hospital, Manisa, Turkey.ORCID 0000-0001-9111-1539
Hüseyin Murat ÖzkanPsychiatry Clinic, Reyap Hospital, Tekirdağ, Turkey.ORCID 0000-0003-0713-1743
Didem Sücüllüoğlu-DikciPsychiatry Clinic, Manisa Mental Health and Diseases Hospital, Manisa, Turkey.ORCID 0000-0003-0473-6675
Kadir AşçibaşiDepartment of Psychiatry, Tepecik Training and Research Hospital, İzmir, Turkey.ORCID 0000-0002-5295-512X
Deniz AlçiPsychiatry Clinic, Balıkesir State Hospital, Balıkesir, Turkey.ORCID 0000-0001-5889-691X
Neslihan AltunsoyPsychiatry Clinic, Boylam Psychiatry Institute, Ankara, Turkey.ORCID 0000-0003-1949-4007
Erkan KuruPsychiatry Clinic, Boylam Psychiatry Institute, Ankara, Turkey.ORCID 0000-0003-1949-4007
Serra YüzerenPsychiatry Clinic, Menemen State Hospital, İzmir, Turkey.ORCID 0000-0002-4728-7331
Ömer AydemirDepartment of Psychiatry, Manisa Celal Bayar University Hospital, Manisa, Turkey.ORCID 0000-0003-3050-1263

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Objective: Cognitive dysfunction is one of the core components of major depressive disorder (MDD). It is estimated that two-thirds of patients diagnosed with MDD have cognitive deficits. Cognitive symptoms are pervasive and affect functioning in several domains. This 16-week prospective case-control study aimed to assess the change of mood and cognitive symptoms during treatment. Materials and Methods: Ninety-eight patients with MDD and 113 healthy controls (HCs) participated in the study. The MDD group was evaluated 6 times (baseline, 2 Results: At baseline, compared with the HCs, the neurocognitive function of patients with MDD was worse. From the 8 Conclusion: Our longitudinal research revealed that even though mood symptoms decreased and patients with depression did achieve symptomatic remission, their cognitive deficits perpetuated.

Indexed as

Cognitioncognitive dysfunctiondepressionmajor depressive disorderneurocognitive function

Identifiers

PMID39619350
PMCPMC11605319

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.