ArticleJACC. Basic to translational science2024
Endothelial Shear Stress Metrics Associate With Proinflammatory Pathways at the Culprit Site of Coronary Erosion.
Article in JACC. Basic to translational science, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
10 citing papers in PubMed.
- Haemodynamic predictors of lesion progression in non-ischaemic tandem coronary stenoses.AsiaIntervention · 2026Article
- Microcalcification: Effects on Atherosclerotic Vulnerable Plaques, Detection, and Therapeutic Perspectives.Current atherosclerosis reports · 2026Review
- Pathogenesis of plaque erosion.Trends in cardiovascular medicine · 2026Review
- Myocardial infarction, stroke and arterial stenosis: time to reassess a major misunderstanding.Nature reviews. Cardiology · 2026Review
- Preclinical serial shear stress analysis of a novel strut-free fibrillated bioresorbable polymeric endoluminal graft.Frontiers in cardiovascular medicine · 2026Article
- Multidimensional optimization of stent design for endothelial shear stress regulation: Geometric structuring, surface functionalization strategies to mitigate thrombosis and restenosis.International journal of cardiology. Heart & vasculature · 2025Review
- Biomarkers Differentiating Plaque Erosion from Stable Plaque.Current atherosclerosis reports · 2025Review
- Unraveling atherosclerosis through single-cell RNA sequencing: insights into cellular heterogeneity and disease mechanisms.Einstein (Sao Paulo, Brazil) · 2025Review
- Pericoronary adipose tissue inflammation mediates the atherogenic effects of lipids on multivessel coronary artery disease: a CCTA-based radiomics analysis.Frontiers in cardiovascular medicine · 2025Article
- Linking Physiology and Biology in Plaque Erosion: A Gordian Knot.JACC. Basic to translational science · 2024Article
Corrections and comments
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Authors and funding
13 authors.
Funding
Abstract
Low endothelial shear stress (ESS) and associated adverse biomechanical features stimulate inflammation, contribute to atherogenesis, and predispose to coronary plaque disruption. The mechanistic links between adverse flow-related hemodynamics and inflammatory mediators implicated in plaque erosion, however, remain little explored. We investigated the relationship of high-risk ESS metrics to culprit lesion proinflammatory/proatherogenic cells and cytokines/chemokines implicated in coronary plaque erosion in patients with acute coronary syndromes. In eroded plaques, low ESS, high ESS gradient, and steepness of plaque topographical slope associated with increased numbers of local T cells and subsets (CD4
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Registered trials
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