ReviewJournal of nutrition and metabolism2024
Glutamine Supplementation: A Possible Strategy to Help Mitigate Health Risks of Heat-Related Illness.
Review in Journal of nutrition and metabolism, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
4 citing papers in PubMed.
- Immunonutrients for radiation-induced oral mucositis in head and neck cancer: current evidence and future perspectives.Frontiers in immunology · 2026Review
- Alpha-ketoglutarate supplementation ameliorates castor oil-induced diarrhea in mice: in silico and in vivo insights.Brazilian journal of medical and biological research = Revista brasileira de pesquisas medicas e biologicas · 2026Article
- Review
- The Role of the SLC1A5 Transporter on Glutathione Homeostasis and Enterocyte Apoptosis in Chronic Treatment of Rats with Immunosuppressive Drugs.International journal of molecular sciences · 2025Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
A rise in body temperature caused by physical work, including exercise, in a hot climate can lead to heat-related illnesses such as exertional heat exhaustion and stroke. Individuals who work physically demanding occupations in hot environments are at heightened risk of heat injury. The mechanisms that contribute to heat illness resulting from physical work in the heat are complex and include dehydration, tissue ischemia and damage, oxidative stress, and inflammatory events. Therefore, it is important to develop strategies that address these mechanistic underpinnings to prevent exacerbation to heat illness. Glutamine is an amino acid that has been considered conditionally essential during situations of biological stress (e.g., tissue burn, exercise, sepsis) due to high rates of tissue consumption. Evidence suggests that glutamine may serve as an important nutrient during heat stress and when combined with other preventative measures (e.g., cooling techniques, work/rest ratios, clothing) may help to mitigate heat illness among individuals working in extreme climates. The aim of this review is to examine the current literature on the role of glutamine during heat stress.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.