Evidence map›Paper›PMID 39618753›Full record

ArticleCureus2024

A Case of Drug-Induced Lupus in Crohn's Disease During Infliximab Therapy.

Tomotaka Tanaka, Daiki Hirano, Syohei Ishimaru, Keiko Arataki

Abstract readCase Reports
In one paragraph

Article in Cureus, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Tomotaka TanakaDepartment of Gastroenterology, Tsuchiya General Hospital, Hiroshima, JPN.
Daiki HiranoDepartment of Gastroenterology, Tsuchiya General Hospital, Hiroshima, JPN.
Syohei IshimaruDepartment of Gastroenterology, Tsuchiya General Hospital, Hiroshima, JPN.
Keiko AratakiDepartment of Gastroenterology, Tsuchiya General Hospital, Hiroshima, JPN.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

A 46-year-old man with a known case of Crohn's disease, which developed in August 2010, had been in remission since then with infliximab treatment. However, in November 2023, he developed photosensitivity, followed by joint pain and general fatigue in December. Blood tests revealed positive antinuclear antibodies, leading to a diagnosis of drug-induced lupus. After switching from infliximab to vedolizumab, his symptoms improved, and antinuclear antibodies became negative. We present a case of Crohn's disease in which drug-induced lupus developed after approximately 14 years of infliximab treatment. Cases of drug-induced lupus developing from long-term administration of tumor necrosis factor alpha (TNFα) inhibitors are rare, so we report this case with a literature review.

Indexed as

antinuclear antibodycrohn diseasedrug-induced lupus erythematosusinfliximabvedolizumab

Identifiers

PMID39618753
PMCPMC11606730

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.