ArticleCureus2024
Fatal Disseminated Varicella-Zoster Virus in an Immunocompetent Woman.
Article in Cureus, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
0 citing papers in PubMed.
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Authors and funding
4 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Disseminated herpes zoster (DHZ), caused by the reactivation of latent varicella-zoster virus (VZV), is usually a condition that affects the immunocompromised population. It is uncommon in a vaccinated population. A previously well, independent 91-year-old lady with no known immunosuppressing conditions presented to the hospital with a productive cough and new confusion. Several days into her admission, she developed a cutaneous maculopapular rash, and then symptoms of headache and seizures, followed by a coma. This coincided with the development of extensive neuroimaging findings, including widespread vasogenic edema and mass effect. Despite treatment with intravenous antiviral therapy, she deteriorated and passed away, with a retrospective diagnosis of DHZ. This case illustrates rapid progression of VZV infection and potential for fatality in elderly, unvaccinated but immunocompetent individuals. It provides a reminder of the importance of maintaining a degree of clinical suspicion for the diagnosis of DHZ in those with suggestive features, especially in unvaccinated individuals.
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