ArticleCureus2024
Spontaneous Tumor Lysis Syndrome in the Setting of Pancreatic Adenocarcinoma.
Article in Cureus, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
0 citing papers in PubMed.
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Authors and funding
5 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Tumor lysis syndrome (TLS) is the destruction of tumor cells, causing the release of intracellular contents, including but not limited to uric acid, phosphate, and potassium. This can manifest with significant physiologic abnormalities, such as life-threatening acute kidney injury. Although TLS is usually caused by the initiation of cytotoxic chemotherapy, it may also occur spontaneously, particularly in high-grade malignancies with high tumor burden and/or rapid cell turnover. Here, we present a case of spontaneous TLS in a patient with early-phase pancreatic cancer diagnosis and possible signs of metastasis. Additionally, we provide a comprehensive review of the current literature regarding this phenomenon. In the present case, our patient was stabilized using aggressive intravenous hydration and pharmacotherapy. This case report adds to the slowly growing literature surrounding the diagnosis and management of spontaneous TLS in pancreatic adenocarcinomas.
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Registered trials
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