Evidence map›Paper›PMID 39618439›Full record

ArticleJournal of maxillofacial and oral surgery2024

Does a Single Episode of Pain from Impacted Third Molars Necessitate Their Removal?

Havilah K Deepthi, Kishore Moturi, Puvvada Divya, U Shivaji Raju, R S G Satya Sai, Naga Sai Reddy, Prasanna Patruni

Abstract read
In one paragraph

Article in Journal of maxillofacial and oral surgery, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Havilah K DeepthiGuntur, Andhra Pradesh India.ORCID 0000-0003-0324-0627
Kishore MoturiDepartment of Oral and Maxillofacial Surgery, Vishnu Dental College, Bhimavaram, West Godavari District, Andhra Pradesh 534202 India.ORCID 0000-0002-5771-2397
Puvvada DivyaDepartment of Oral and Maxillofacial Surgery, Vishnu Dental College, Bhimavaram, West Godavari District, Andhra Pradesh 534202 India.ORCID 0000-0001-5945-9412
U Shivaji RajuDepartment of Oral and Maxillofacial Surgery, Vishnu Dental College, Bhimavaram, West Godavari District, Andhra Pradesh 534202 India.ORCID 0000-0001-6347-5781
R S G Satya SaiDepartment of Oral and Maxillofacial Surgery, Vishnu Dental College, Bhimavaram, West Godavari District, Andhra Pradesh 534202 India.ORCID 0000-0003-4578-9335
Naga Sai ReddyDepartment of Oral and Maxillofacial Surgery, Vishnu Dental College, Bhimavaram, West Godavari District, Andhra Pradesh 534202 India.ORCID 0000-0002-4012-6711
Prasanna PatruniDepartment of Oral and Maxillofacial Surgery, Vishnu Dental College, Bhimavaram, West Godavari District, Andhra Pradesh 534202 India.ORCID 0000-0002-0410-4873

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Pericoronitis induces oxidative stress in the dental follicular (DF) tissue, which can lead to histopathological alterations. It is a fact that an impacted tooth with a history of recurrent pericoronitis should be extracted. But there is a limited research on the levels of nitric oxide (NO) in DF tissues of impacted mandibular third molars with even a single episode of pain, necessitating their removal biochemically at a younger age. A cross-sectional study was designed to assess and compare the levels of nitric oxide in DF tissues of impacted mandibular third molars without a history of pain to those with a history of a single episode of pain in the past six months. Materials and Methods: Sixty individuals with impacted third molars were enrolled in a single-blind cross-sectional study. Group A ( Results: Nitric oxide levels were significantly higher for patients with a history of a single episode of pain in the past six months than those without any history of pain ( Conclusion: The findings of this study suggest that NO could be used as an indicator of oxidative stress and therefore emphasizes the importance of removing impacted mandibular third molars in patients who have had even a single episode of pain.

Indexed as

InflammationMandibular third molarNitric oxidePericoronitis

Identifiers

PMID39618439
PMCPMC11607293

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.