ArticleEuroIntervention : journal of EuroPCR in collaboration with the Working Group on Interventional Cardiology of the European Society of Cardiology2024
Outcomes of coronary intravascular lithotripsy for the treatment of calcified nodules: a pooled analysis of the Disrupt CAD studies.
Article in EuroIntervention : journal of EuroPCR in collaboration with the Working Group on Interventional Cardiology of the European Society of Cardiology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.
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Who cites it
10 citing papers in PubMed.
- Review
- Coronary Intravascular Lithotripsy in Clinical Practice.Journal of clinical medicine · 2026Review
- Coronary Calcified Nodules: From Pathological Definitions to Intravascular Imaging- and Morphology-Guided PCI.International journal of molecular sciences · 2026Review
- Dual-Prep registry: Atherectomy devices and intravascUlAr lithotripsy for the PREParation of heavily calcified coronary lesions registry, 1-year results.Cardiovascular intervention and therapeutics · 2026Article
- Intravascular lithotripsy for recurrent restenosis caused by a calcified nodule in a saphenous vein graft: a case report.European heart journal. Case reports · 2026Article
- Intravascular lithotripsy versus rotational atherectomy for coronary atherosclerosis calcification: a systematic review and meta-analysis.The Egyptian heart journal : (EHJ) : official bulletin of the Egyptian Society of Cardiology · 2026Review
- A patient-tailored percutaneous coronary intervention of calcified lesions using different intravascular lithotripsy modalities in a multimorbid nonagenarian patient presenting with non-ST elevation myocardial infarction.Postepy w kardiologii interwencyjnej = Advances in interventional cardiology · 2026Article
- Article
- Calcified Nodules: Pathology, Mechanisms, and Clinical Challenges.Current cardiology reports · 2025Review
- Case Report: Overcoming calcified nodules by repeated aggressive debulking and stent-free percunatenous coronary intervention using a drug-coated balloon.Frontiers in cardiovascular medicine · 2025Article
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Authors and funding
18 authors.
Funding
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Abstract
backgroundCoronary intravascular lithotripsy (IVL) safely facilitates stent implantation in severely calcified lesions.
aimsThis analysis sought to determine the relative impact of IVL on acute and long-term outcomes specifically in calcified nodules (CNs).
methodsIndividual patient-level data (N=155) were pooled from the Disrupt CAD optical coherence tomography (OCT) substudies. Severely calcified lesions with and without CNs were compared by OCT for acute procedural results and for target lesion failure (TLF) at 2 years - a composite of cardiac death, target vessel myocardial infarction, and ischaemia-driven target lesion revascularisation.
resultsA CN was identified in 18.7% (29/155) of lesions. When comparing lesions with and without CNs, there were no significant differences in preprocedure minimal lumen area or diameter stenosis; however, the mean calcium angle and calcium volume were greater in CN lesions. Despite a higher calcium burden, the final minimal stent area (CN: 5.7 mm
conclusionsDespite a greater calcium volume in CNs, IVL use was associated with comparable stent expansion and luminal gain in both CN and non-CN lesions. Further studies powered for clinical outcomes comparing different plaque modification techniques in this lesion subset are warranted.
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