Evidence map›Paper›PMID 39618165›Full record

ArticleESC heart failure2025

Inter-atrial block as a predictor of adverse outcomes in patients with HFpEF.

Jerremy Weerts, Sanne G J Mourmans, Helena Lopez-Martinez, Mar Domingo, Arantxa Barandiarán Aizpurua, Michiel T H M Henkens, Anouk Achten, Josep Lupón, Hans-Peter Brunner-La Rocca, Christian Knackstedt and 2 more

Abstract readMulticenter Study
PubMed Full text at PMC Publisher
In one paragraph

Article in ESC heart failure, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Non-invasive assessment of left atrial activation using lead V8 during Bachmann bundle pacing.Europace : European pacing, arrhythmias, and cardiac electrophysiology : journal of the working groups on cardiac pacing, arrhythmias, and cardiac cellular electrophysiology of the European Society of Cardiology · 2026
    Article
  2. Review
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Jerremy WeertsDepartment of Cardiology, Cardiovascular Research Institute Maastricht (CARIM), Maastricht University Medical Centre+ (MUMC+), Maastricht, The Netherlands.
Sanne G J MourmansDepartment of Cardiology, Cardiovascular Research Institute Maastricht (CARIM), Maastricht University Medical Centre+ (MUMC+), Maastricht, The Netherlands.ORCID https://orcid.org/0000-0003-3408-6511
Helena Lopez-MartinezHeart Institute, Hospital Universitari Germans Trias i Pujol, Barcelona, Spain.
Mar DomingoHeart Institute, Hospital Universitari Germans Trias i Pujol, Barcelona, Spain.
Arantxa Barandiarán AizpuruaDepartment of Cardiology, Cardiovascular Research Institute Maastricht (CARIM), Maastricht University Medical Centre+ (MUMC+), Maastricht, The Netherlands.
Michiel T H M HenkensDepartment of Cardiology, Cardiovascular Research Institute Maastricht (CARIM), Maastricht University Medical Centre+ (MUMC+), Maastricht, The Netherlands.
Anouk AchtenDepartment of Cardiology, Cardiovascular Research Institute Maastricht (CARIM), Maastricht University Medical Centre+ (MUMC+), Maastricht, The Netherlands.
Josep LupónHeart Institute, Hospital Universitari Germans Trias i Pujol, Barcelona, Spain.
Hans-Peter Brunner-La RoccaDepartment of Cardiology, Cardiovascular Research Institute Maastricht (CARIM), Maastricht University Medical Centre+ (MUMC+), Maastricht, The Netherlands.
Christian KnackstedtDepartment of Cardiology, Cardiovascular Research Institute Maastricht (CARIM), Maastricht University Medical Centre+ (MUMC+), Maastricht, The Netherlands.
Antoni Bayés-GenísHeart Institute, Hospital Universitari Germans Trias i Pujol, Barcelona, Spain.
Vanessa P M van EmpelDepartment of Cardiology, Cardiovascular Research Institute Maastricht (CARIM), Maastricht University Medical Centre+ (MUMC+), Maastricht, The Netherlands.

Funding

Dutch Heart FoundationHealth Foundation Limburg
6 · The paper itself

Abstract

aimsInter-atrial block (IAB), a marker of electrical atrial dysfunction, is associated with an increased risk of atrial fibrillation (AF) and adverse events in various populations. The prognostic impact of IAB in heart failure (HF) with preserved ejection fraction (HFpEF) remains unknown. The aim of this study is to determine the prevalence of IAB and the association of IAB and AF with adverse events in HFpEF across different healthcare settings. METHODS AND

resultsTo identify electrical atrial dysfunction, baseline ECG's and medical history were analysed in HFpEF patients in an ambulatory setting and after recent HF hospitalisation. Patients were categorised into (i) HFpEF

conclusionsProgressive stages of electrical atrial dysfunction appeared to be prognostic markers of adverse outcomes in ambulatory and recently hospitalised patients with HFpEF. Ambulatory patients with HFpEF and no early stages of electrical atrial dysfunction showed to be at very low risk for adverse outcomes. Whether such patients benefit less strict management remains to be investigated.

Indexed as

Heart AtriaHeart FailureInteratrial BlockStroke VolumeAgedAged, 80 and overAtrial FibrillationElectrocardiographyFemaleFollow-Up StudiesHospitalizationHumansMalePrognosisRetrospective StudiesRisk FactorsAtrial dysfunctionAtrial fibrillationElectrocardiographyHeart atriaHeart failure with preserved ejection fractionPrognosis

Identifiers

PMID39618165
PMCPMC12055423

What OpenQuestion holds

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LicenceCC BY-NC-ND
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.