Observational studyActa obstetricia et gynecologica Scandinavica2025
Mode of delivery and outcomes among inborn extremely preterm singletons: A cohort study.
Observational study in Acta obstetricia et gynecologica Scandinavica, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
2 citing papers in PubMed.
- Spatial scanning for the identification of risk areas for fetal death: an ecological study in Pernambuco.Revista da Escola de Enfermagem da U S P · 2026Article
- Mode of delivery and outcomes among inborn extremely preterm singletons: A cohort study.Acta obstetricia et gynecologica Scandinavica · 2025Observational
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Authors and funding
11 authors.
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Abstract
introductionCesarean delivery is the most common mode of delivery among extremely preterm infants but there are insufficient data regarding the best mode of delivery among extremely preterm singletons. The objective of this study was to compare the rate of death or severe neurodevelopmental impairment among extremely preterm singletons by actual mode of delivery. MATERIAL AND
methodsObservational study using prospectively collected data from 25 US medical centers. We included postnatally-treated singletons with birth weight 401-1000 g, gestational age 22 + 0/7-26 + 6/7 weeks, without a major birth defect, born 2006-2016. Death or severe neurodevelopmental impairment (Bayley Scales of Infant Development-3rd edition cognitive composite score<70, cerebral palsy (Gross Motor Function Classification Scale >3), bilateral blindness, or bilateral hearing loss) at 18-26 month follow-up were compared by mode of delivery (cesarean, vaginal including vertex or breech) using propensity score analysis to adjust for baseline characteristics.
resultsThere was no difference in death or severe neurodevelopmental impairment between cesarean and vaginal (vertex or breech) births (42.4% cesarean vs. 47.2% vaginal; adjusted odds ratio (aOR), 95% confidence intervals (CI); 1.03, 0.91-1.17). Both cesarean delivery (26.8% cesarean vs. 51.5% breech vaginal; aOR: 0.71; 95% CI: 0.55-0.92) and vertex vaginal delivery (28.5% vertex vaginal vs. 51.5% breech vaginal; aOR: 0.59; 95% CI: 0.45-0.76) were associated with lower mortality compared with breech vaginal delivery.
conclusionsAmong postnatally-treated extremely preterm singletons, there was no difference in death or severe neurodevelopmental impairment between cesarean or vaginal delivery. Both vertex vaginal and cesarean delivery were associated with lower mortality compared with breech vaginal delivery.
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