ArticleAnnals of medicine2024
HER-2 expression is correlated with multimodal imaging features in breast cancer: a pilot study.
Article in Annals of medicine, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.
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Who cites it
3 citing papers in PubMed.
- Trastuzumab deruxtecan in advanced breast cancer: a real-world study of efficacy and safety in Chinese cohort with HER2-positive and HER2-low expression.Frontiers in oncology · 2026Article
- Preoperative prediction of breast cancer Ki-67 status via multimodal ultrasound-clinical nomogram: a single-center study.Translational cancer research · 2025Article
- Lidocaine suppresses HER2-positive breast cancer cell proliferation by targeting the OGT-CCNL1 axis.Discover oncology · 2025Article
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Authors and funding
8 authors.
Funding
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Abstract
objectiveA pilot study to evaluate the correlation between multimodal imaging features and the expression of the human epidermal growth factor receptor type 2 (HER-2) in breast cancer to provide a basis for clinical treatment and prognosis evaluation.
methodsWe included a total of 62 patients with breast cancer admitted to the Affiliated Hospital of Hebei University between 2018 and 2022. All of them underwent the relevant investigations, including ultrasound, mammography, and enhanced magnetic resonance imaging (MRI), in the hospital within one month before surgery or biopsy. HER-2 expression level was divided into negative and positive by immunohistochemistry(IHC). Using SPSS 24.0 statistical software to analyze the differences in imaging features between the HER-2 positive and the HER-2 negative groups.
resultsThere was a statistically significant difference between the HER-2 positive and the HER-2 negative groups (
conclusionA combination of multimodal imaging features and HER-2 gene expression can provide more valuable information for clinical diagnosis and therapeutic schedule in breast cancer.
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