Evidence map›Paper›PMID 39618048›Full record

Trial reportSubstance use & misuse2025

Recovery Capital and Subsequent Overdose Risk and Addiction Treatment Engagement Among Emergency Department Patients at High Risk of Opioid Overdose.

Laura C Chambers, Ralph A Welwean, Daniel K Cho, Kirsten J Langdon, Yu Li, Benjamin D Hallowell, Mackenzie M Daly, Brandon D L Marshall, Francesca L Beaudoin

Abstract readRandomized Controlled Trial
In one paragraph

Trial report in Substance use & misuse, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Laura C ChambersDepartment of Epidemiology, Brown University School of Public Health, Providence, Rhode Island.ORCID 0000-0003-1802-6578
Ralph A WelweanDepartment of Epidemiology, Brown University School of Public Health, Providence, Rhode Island.
Daniel K ChoAlpert Medical School of Brown University, Providence, Rhode Island.
Kirsten J LangdonDepartment of Psychiatry, Rhode Island Hospital, Providence, Rhode Island.
Yu LiDepartment of Epidemiology, Brown University School of Public Health, Providence, Rhode Island.
Benjamin D HallowellSubstance Use Epidemiology Program, Rhode Island Department of Health, Providence, Rhode Island.ORCID 0000-0002-6943-9615
Mackenzie M DalyResearch, Data Evaluation, and Compliance Unit; Rhode Island Department of Behavioral Healthcare, Developmental Disabilities, and Hospitals; Providence, Rhode Island.
Brandon D L MarshallDepartment of Epidemiology, Brown University School of Public Health, Providence, Rhode Island.
Francesca L BeaudoinDepartment of Epidemiology, Brown University School of Public Health, Providence, Rhode Island.

Funding

Translational ScienceP30AI042853 · NIAID · MIRIAM HOSPITAL · PI CURT G BECKWITH, DEBBIE M. CHENG · 1998 to 2026
$51.7M
Project 4: Neonatal Abstinence Syndrome (NAS): Fetus to First YearsP20GM125507 · NIGMS · RHODE ISLAND HOSPITAL · PI CURT G BECKWITH · 2018 to 2026
$23.4M
Integrated Digital Health Intervention to Promote Engagement in and Adherence to Medication-Assisted TreatmentK23DA046482 · NIDA · RHODE ISLAND HOSPITAL · PI LANGDON, KIRSTEN JOHNSON · 2019 to 2023
$911k
NIAID NIH HHS P30 AI042853NIDA NIH HHS K23 DA046482NIGMS NIH HHS P20 GM125507
6 · The paper itself

Abstract

backgroundEmergency department (ED) visits are an opportunity to provide prevention services to people at high risk of overdose. Considering patients' resources to initiate and sustain recovery ("recovery capital") may be useful for tailoring ED services, although its relevance in this population is unknown.

methodsThis secondary analysis used data from ED patients at high risk of opioid overdose enrolled in a randomized controlled trial in Rhode Island (2018-2021). We assessed baseline recovery capital using the Brief Assessment of Recovery Capital (BARC-10), dichotomized as a total score <47 versus ≥47. Post-discharge addiction treatment engagement within 30 days and non-fatal opioid overdose and fatal overdose within 18 months were assessed using statewide administrative data. We used modified Poisson regression and Cox proportional hazards models to estimate the association between recovery capital and (1) treatment engagement and (2) overdose risk, respectively, adjusting for potential confounders.

resultsAmong 543 participants, 32.2% had a baseline BARC-10 total score of ≥47, 32.6% engaged in treatment within 30 days, and 25.6% had a non-fatal opioid overdose and 4.2% had a fatal overdose within 18 months. BARC-10 total score was not associated with treatment engagement within 30 days (adjusted relative risk = 0.79, 95% confidence interval [CI] = 0.60-1.05) or non-fatal opioid overdose (adjusted hazard ratio [aHR] = 0.83, 95%CI = 0.57-1.20) or fatal overdose (aHR = 0.45, 95%CI = 0.14-1.40) within 18 months.

conclusionThe majority of ED patients at high risk of opioid overdose had a BARC-10 total score of <47, suggesting low recovery capital. BARC-10 total score was not associated with post-discharge treatment engagement or overdose risk.

Indexed as

Drug OverdoseEmergency Service, HospitalOpiate OverdoseOpioid-Related DisordersAdultFemaleHumansMaleMiddle AgedRhode IslandRisk FactorsYoung Adultaddiction treatmentemergency medicineopioid use disorderoverdoseRecovery capitalsubstance use disorder

Identifiers

PMID39618048
PMCPMC11769765

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.