Evidence map›Paper›PMID 39617931›Full record

ArticleEye and vision (London, England)2024

Establishing an objective decision criterion for intraocular lens exchange due to homogeneous calcification: a prospective clinical analysis.

Timur M Yildirim, Grzegorz Łabuz, Nikola Henningsen, Hyeck-Soo Son, Victor A Augustin, Leoni Britz, Lizaveta Chychko, Ramin Khoramnia, Gerd U Auffarth

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Article in Eye and vision (London, England), 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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1 · What the graph read from it

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2 · The registry

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3 · Its place in the literature

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4 · The record

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5 · Who and what money

Authors and funding

9 authors.

Timur M YildirimDavid J Apple Center for Vision Research, Department of Ophthalmology, University of Heidelberg, Im Neuenheimer Feld 400, 69120 , Heidelberg, Germany. timur.yildirim@med.uni-heidelberg.de.ORCID http://orcid.org/0000-0002-3687-5082
Grzegorz ŁabuzDavid J Apple Center for Vision Research, Department of Ophthalmology, University of Heidelberg, Im Neuenheimer Feld 400, 69120 , Heidelberg, Germany.
Nikola HenningsenDavid J Apple Center for Vision Research, Department of Ophthalmology, University of Heidelberg, Im Neuenheimer Feld 400, 69120 , Heidelberg, Germany.
Hyeck-Soo SonDavid J Apple Center for Vision Research, Department of Ophthalmology, University of Heidelberg, Im Neuenheimer Feld 400, 69120 , Heidelberg, Germany.
Victor A AugustinDavid J Apple Center for Vision Research, Department of Ophthalmology, University of Heidelberg, Im Neuenheimer Feld 400, 69120 , Heidelberg, Germany.
Leoni BritzDavid J Apple Center for Vision Research, Department of Ophthalmology, University of Heidelberg, Im Neuenheimer Feld 400, 69120 , Heidelberg, Germany.
Lizaveta ChychkoDavid J Apple Center for Vision Research, Department of Ophthalmology, University of Heidelberg, Im Neuenheimer Feld 400, 69120 , Heidelberg, Germany.
Ramin Khoramnia *David J Apple Center for Vision Research, Department of Ophthalmology, University of Heidelberg, Im Neuenheimer Feld 400, 69120 , Heidelberg, Germany.
Gerd U Auffarth *David J Apple Center for Vision Research, Department of Ophthalmology, University of Heidelberg, Im Neuenheimer Feld 400, 69120 , Heidelberg, Germany.

Funding

European Society of Cataract and Refractive Surgeons IOLExcg.
6 · The paper itself

Abstract

backgroundHomogeneous intraocular lens (IOL) calcification deteriorates patient's visual quality. There is a lack of functional and patient-reported data on patients with this material change undergoing IOL exchange surgery. The aim of this study was to evaluate subjective and objective outcomes following IOL exchange due to homogeneous IOL calcification to improve evidence-based patient counseling.

methodsIn this prospective, non-interventional, clinical study, 53 eyes of 42 patients with homogeneous IOL calcification were included. IOL exchange was performed in 30 out of 53 eyes. Subjective symptoms using a quality-of-life questionnaire (Catquest-9SF), photic phenomena, corrected distance visual acuity (CDVA), straylight (C-Quant, Oculus, Wezlar, Germany) and contrast sensitivity with and without glare (CSV-1000, VectorVision, Houston, USA) were assessed before (T0) and at 3 to 12 months after IOL exchange (T1).

resultsPreoperative CDVA and straylight did not correlate. Average halo and glare size and intensity decreased and Catquest-9SF items improved. The CDVA rose significantly from 0.16 ± 0.13 to 0.05 ± 0.10 logMAR, and contrast sensitivity increased with and without glare. The straylight value decreased statistically and clinically significant from 2.32 ± 0.34 to 1.23 ± 0.33 log(s).

conclusionHomogeneous IOL calcification is not always associated with a pronounced reduction in visual acuity. In most cases, IOL exchange still reduces subjective complaints and improves quality of vision of affected patients. Visual acuity should not be the sole functional parameter in assessing patients with homogeneous IOL calcification as intraocular straylight and contrast sensitivity can better objectify patients' visual impairment. We recommend a straylight value above 1.56 log(s) as a cut-off when deciding on an IOL exchange surgery.

Indexed as

Cataract surgeryContrast sensitivityIOL complicationIOL exchangeIOL materialPatient reported outcomePrimary IOL calcificationStraylightVisual quality

Identifiers

PMID39617931
PMCPMC11610101

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.