Evidence map›Paper›PMID 39617697›Full record

ArticleJournal of traditional Chinese medicine = Chung i tsa chih ying wen pan2024

Renshen (Radix Ginseng) polysaccharide promotes repair of the mice intestinal mucosa through regulatory mechanisms based on polyamine and human antigen R.

Wang Guanyu, Dai Xingzhen, Liu Yiting, Zhu Zeming, H U Ling, L I Ruliu

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Journal of traditional Chinese medicine = Chung i tsa chih ying wen pan, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Wang GuanyuScience and Technology Innovation Center, Guangzhou University of Chinese Medicine, Guangzhou 510405, China.
Dai XingzhenScience and Technology Innovation Center, Guangzhou University of Chinese Medicine, Guangzhou 510405, China.
Liu YitingScience and Technology Innovation Center, Guangzhou University of Chinese Medicine, Guangzhou 510405, China.
Zhu ZemingScience and Technology Innovation Center, Guangzhou University of Chinese Medicine, Guangzhou 510405, China.
H U LingScience and Technology Innovation Center, Guangzhou University of Chinese Medicine, Guangzhou 510405, China.
L I RuliuScience and Technology Innovation Center, Guangzhou University of Chinese Medicine, Guangzhou 510405, China.

Funding

First-class Discipline Construction Major Project of Guangzhou University of Chinese Medicine, Guangzhou University of Chinese Medicine Planning (2020) No. 62: based on the Viscous Characteristics of Dampness and Pathogenic Factors in Lingnan, this Paper Studied the Differential Characteristics of the Syndrome of Deficiency of Spleen and Stomach Disease and the Intervention Mechanism of Lingnan Traditional Chinese Medicine for Mucosal Damage Repair 62National Natural Science Foundation of China: Study on the Effect of Supplementing Qi and Invigorating the Spleen on the Migration of Small Intestinal Epithelial Cells through the Regulation of Polyamines and Calcium Ions 81673940
6 · The paper itself

Abstract

objectiveTo investigate the mechanism and effect of Renshen (

methodsMice were fed 3% (w/v) DSS for 6 d to create colonic lesions. A cell-migration model was created using cell scratching. mRNA expression, protein expression, translation efficiency of mRNA, and nucleoplasmic distribution of human antigen R (HuR) were determined by real-time reverse transcription-quantitative polymerase chain reaction, western blotting, a dual luciferase reporter system, and immunofluorescence staining, respectively.

resultsRenshen (

conclusionsRenshen (

Indexed as

Cell MovementIntestinal MucosaPanaxPolysaccharidesAnimalscdc42 GTP-Binding ProteinCell LineDrugs, Chinese HerbalELAV-Like Protein 1HumansMaleMiceMice, Inbred C57BLRatscdc42 GTP-Binding ProteinDrugs, Chinese HerbalELAV-Like Protein 1Polysaccharidescell movementhuman antigen Rintestinal mucosal damage repairpolysaccharidespost-transcriptional regulationRenshen ()

Identifiers

PMID39617697
PMCPMC11589556

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.