ArticleThe Journal of veterinary medical science2025
First detection of NADC34-like porcine reproductive and respiratory syndrome virus strains in Japan.
Article in The Journal of veterinary medical science, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.
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Who cites it
5 citing papers in PubMed.
- Immunopathogenesis and pathological features of NADC34-like PRRSV infection in pregnant sows during late gestation.Veterinary research · 2026Article
- Nationwide emergence and spread of highly virulent PRRSV-2 mutants in Korea.Porcine health management · 2025Article
- Genetic Diversity and Temporal Shifts of Porcine Reproductive and Respiratory Syndrome Virus Type 2 (PRRSV-2) Strains in Japan (2020-2023): Evidence of Modified Live Vaccine Influence on Cluster Distribution.Epidemiologia (Basel, Switzerland) · 2025Article
- Porcine reproductive and respiratory syndrome virus type 1 and type 2 co-infection in a Japanese swine herd.The Journal of veterinary medical science · 2025Article
- Epidemiological Review of Porcine Reproductive and Respiratory Syndrome Virus (PRRSV) in Japan: From Discovery and Spread to Economic Losses and Future Prospects.Veterinary sciences · 2025Review
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Authors and funding
5 authors.
Funding
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Abstract
Porcine reproductive and respiratory syndrome virus (PRRSV) is an important pathogen in the swine industry. We report for the first time the detection of NADC34-like PRRSV strains in Japan. Serum samples from 18 piglets in Okinawa Prefecture were analyzed for the open reading frame 5 (ORF5) gene encoding glycoprotein 5, which revealed that all samples belonged to sublineage 1.5 (L1A) of Lineage 1. Phylogenetic analysis, restriction fragment length polymorphism patterns, and glycosylation site characteristics confirmed the presence of NADC34-like strains that caused severe outbreaks in the U.S. and Asia. Despite its known pathogenicity, the farm showed only a transient increase in mortality. These findings highlight the need for further investigation into the pathogenicity of PRRSV strains and their potential for the emergence of new variants in Japan.
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