Evidence map›Paper›PMID 39616991›Full record

Observational studyDementia and geriatric cognitive disorders2025

Screening for Cognitive Impairment in the Emergency Department: Agreement between Older Adult Patient- and Informant-Completed Ascertain Dementia 8 Tool.

James Galske, Anna Sather, Tonya Chera, Ula Hwang, Christopher R Carpenter, Matthew Babcock, Cameron J Gettel

Abstract readObservational Study
In one paragraph

Observational study in Dementia and geriatric cognitive disorders, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Recruiting People With Dementia in Emergency Research: Insights From Geriatric Emergency Care Applied Research 2.0 Network (GEAR 2.0) Pilot Studies.Academic emergency medicine : official journal of the Society for Academic Emergency Medicine · 2026
    Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

James GalskeDepartment of Emergency Medicine, Yale School of Medicine, New Haven, Connecticut, USA.
Anna SatherIcahn School of Medicine at Mount Sinai, New York, New York, USA.
Tonya CheraDepartment of Emergency Medicine, Yale School of Medicine, New Haven, Connecticut, USA.
Ula HwangDepartments of Emergency Medicine and Population Health, New York University, New York, New York, USA.
Christopher R CarpenterDepartment of Emergency Medicine, Mayo Clinic, Rochester, Minnesota, USA.
Matthew BabcockDepartment of Emergency Medicine, University of Connecticut Health Center, Farmington, Connecticut, USA.
Cameron J GettelDepartment of Emergency Medicine, Yale School of Medicine, New Haven, Connecticut, USA.

Funding

Training Core (I)U54AG063546 · NIA · BROWN UNIVERSITY · PI Alexia Mary Torke · 2019 to 2026
$125.9M
Yale Study Support Suite (YES3): Dashboard and Web Portal Software Supporting Research Workflow through integrated, customizable REDCap External ModulesP30AG021342 · NIA · YALE UNIVERSITY · PI Lauren Ferrante · 2002 to 2026
$37.9M
Geriatrics Emergency care Applied Research Network 2.1 - AdvanCing and Expanding Dementia care (GEAR 2.1 - ACED)R33AG069822 · NIA · YALE UNIVERSITY · PI Ula Y Hwang, MANISH N SHAH · 2023 to 2026
$5.3M
Growing the Geriatric Emergency care Applied Research (GEAR 1.1) network: Expanding and sustaining an emergency care aging study infrastructure.R33AG058926 · NIA · YALE UNIVERSITY · PI Ula Y Hwang, Daniella Meeker · 2020 to 2026
$4.6M
Development and validation of the Patient-Reported Outcome Measure - Older adult care Transitions from the Emergency Department (PROM-OTED) toolR03AG073988 · NIA · YALE UNIVERSITY · PI GETTEL, CAMERON · 2021 to 2022
$335k
Physician Scientists in Aging: Developing and Activating Specialty InvestigatorsU13AG048721 · NIA · AMERICAN GERIATRICS SOCIETY · PI CARPENTER, CHRISTOPHER ROBERT · 2014 to 2018
$208k
NIA NIH HHS P30 AG021342NIA NIH HHS R03 AG073988NIA NIH HHS R33 AG058926NIA NIH HHS R33 AG069822NIA NIH HHS U13 AG048721NIA NIH HHS U54 AG063546
6 · The paper itself

Abstract

introductionEmergency department (ED) screening for cognitive impairment (CI) is crucial for early intervention, yet guidance on dementia screening protocols remains limited. Our objective was to assess the concordance between the Ascertain Dementia 8 (AD8) tool, a brief screening tool for CI, administered to ED patients and their informants.

methodsWe conducted a prospective observational study of dyads, including patients ≥65 years without a diagnosis of dementia seeking care in the ED and their informants (e.g., family, friend with close contact). Trained research assistants used the 4AT to exclude patients with concern for delirium. The AD8 was then administered to blinded patients (pAD8) and informants (iAD8), with scores ranging from 0 to 8 and scores of ≥2 indicating CI. We used the intraclass correlation coefficient (ICC) to calculate the level of agreement between AD8 scores.

resultsOur analytic sample included 538 dyads, of which 63.3% of patients were female with a mean age of 73.5 years. A total of 131 (24.3%) patients without a diagnosis of dementia self-identified as having CI using the pAD8, in comparison to 110 (20.4%) informants using the iAD8. The ICC of 0.519 (95% CI 0.454-0.578) indicated moderate agreement between pAD8 and iAD8 scores.

conclusionsWhen seeking emergency care, one in four older adults without a diagnosis of dementia and approximately 20% of informants indicated that patients were cognitively impaired. Our finding of moderate agreement between the pAD8 and iAD8 has important implications for clinicians providing care to patients with suspected CI and investigators conducting dementia-related studies.

Indexed as

Cognitive DysfunctionDementiaEmergency Service, HospitalAgedAged, 80 and overFemaleHumansMaleMass ScreeningMental Status and Dementia TestsNeuropsychological TestsProspective StudiesCaregiversCognitive screeningCognitive screening testEmergency departmentMild cognitive impairment and dementia

Identifiers

PMID39616991
PMCPMC12119964

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.