ArticleJournal of applied clinical medical physics2025
Quality and mechanical efficiency of automated knowledge-based planning for volumetric-modulated arc therapy in head and neck cancer.
Article in Journal of applied clinical medical physics, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
3 citing papers in PubMed.
- Artificial intelligence in radiation treatment planning: a narrative review from automation to clinical decision support.Translational cancer research · 2026Review
- Knowledge based automated planning for non-coplanar VMAT stereotactic radiosurgery in ocular malignancies.Journal of applied clinical medical physics · 2026Article
- Quality and mechanical efficiency of automated knowledge-based planning for volumetric-modulated arc therapy in head and neck cancer.Journal of applied clinical medical physics · 2025Article
Corrections and comments
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Authors and funding
9 authors.
Funding
Abstract
objectivesThis study aimed to examine the effectiveness of the automated RapidPlan in assessing plan quality and to explore how beam complexity affects the mechanical performance of volumetric modulated arc therapy for head and neck cancers. MATERIALS AND
methodsThe plans were first generated using automated RapidPlan with scripting application programming interface (API) and then further refined through manual optimization (RP+MP) to improve plan quality. The quality of 20 plans was assessed, taking into account dose statistics and clinical plan acceptability. The impact of beam complexity on mechanical performance was analyzed using parameters such as leaf speed (LS), leaf acceleration (LA), mean-field area (MFA), cross-axis score (CAS), closed leaf score (CLS), small aperture score (SAS), and monitor units per control point (MU/CP). Patient-specific quality assurance (PSQA) was conducted to determine differences between the RP+MP and original plans.
resultsNo differences in the heterogeneity index and conformity number were observed between the RP+MP and original plans. The RP+MP plan was superior to the original plan for sparing the left cochlea, left and right internal auditory canals, chiasm, and left optic nerve. Significant differences (p < 0.05) were identified in CAS, SAS
conclusionThe automated RP with scripting API followed by MP (RP+MP) yielded a high-quality plan in terms of dose statistics and clinical acceptability. The RP+MP plan yielded a higher CAS and SAS compared with the original plan. Nevertheless, there was no significant difference in PSQA between the RP+MP and original plans.
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Registered trials
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