Evidence map›Paper›PMID 39616568›Full record

ArticleMethods in molecular biology (Clifton, N.J.)2025

Spatial Statistics of Three-Dimensional Growth Dynamics of Spindle Microtubules.

Norio Yamashita, Masahiko Morita, Hideo Yokota, Yuko Mimori-Kiyosue

Abstract read
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In one paragraph

Article in Methods in molecular biology (Clifton, N.J.), 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Norio YamashitaImage Processing Research Team, Center for Advanced Photonics, RIKEN, Saitama, Japan.
Masahiko MoritaImage Processing Research Team, Center for Advanced Photonics, RIKEN, Saitama, Japan.
Hideo YokotaImage Processing Research Team, Center for Advanced Photonics, RIKEN, Saitama, Japan.
Yuko Mimori-KiyosueLaboratory for Molecular and Cellular Dynamics, RIKEN Center for Biosystems Dynamics Research, Kobe, Japan. kiyosuey@hirakata.kmu.ac.jp.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The latest high-resolution 3D live-cell imaging technology, lattice light-sheet microscopy (LLSM), has successfully tracked the dynamics of microtubule growth throughout the entire mitotic spindle with unparalleled precision. By using green fluorescent protein-labeled end-binding protein 1 (EB1-GFP) as a marker for growing microtubule ends, LLSM has generated an extensive collection of multidimensional datasets mapping the positions and trajectories of these growing microtubule ends. Processing this data requires statistical analysis in three-dimensional space. This chapter describes the spatial statistical methods developed for this purpose, illustrated with practical examples. Finally, we discuss future prospects for analyzing complex, large-scale image data.

Indexed as

Imaging, Three-DimensionalMicrotubulesSpindle ApparatusGreen Fluorescent ProteinsHumansImage Processing, Computer-AssistedMicroscopy, FluorescenceMicrotubule-Associated ProteinsGreen Fluorescent ProteinsMicrotubule-Associated ProteinsEB1Lattice light-sheet microscopyLLSMMicrotubule dynamicsMitosisSpatial statisticsSpindle

Identifiers

PMID39616568

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.