ArticleLipids in health and disease2024
Association of the atherogenic index of plasma and modified triglyceride-glucose indices with digestive diseases among middle-aged and older population in China.
Article in Lipids in health and disease, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.
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Who cites it
7 citing papers in PubMed.
- Inflammatory, Nutritional, and Atherogenic Profiles Associated with Histologic Activity in Inflammatory Bowel Disease.Biomedicines · 2026Article
- The association of C-reactive protein-triglyceride-glucose index with cardiometabolic multimorbidity in middle-aged and older adults: evidence from two cohort studies.Cardiovascular diabetology · 2026Article
- Association between the cumulative atherogenic index of plasma and cardiometabolic multimorbidity: the mediating effects of the TyG index and body mass index.Lipids in health and disease · 2026Article
- Deciphering the Association Between Homeostatic Model Assessment of Insulin Resistance and Chronic Diarrhea and the Mediating Role of Lymphocyte-to-Monocyte Ratio.The Turkish journal of gastroenterology : the official journal of Turkish Society of Gastroenterology · 2026Article
- Dynapenic Abdominal Obesity and the Risk of Non-Neoplastic Digestive System Diseases in Postmenopausal Women: A Prospective Cohort Study.International journal of women's health · 2026Article
- Associations between nighttime sleep duration trajectories and risk of digestive diseases among middle-aged and older Chinese adults.Sleep & breathing = Schlaf & Atmung · 2025Article
- Observational
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6 authors.
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Abstract
backgroundPrevious studies have shown that metabolic imbalances contribute to digestive diseases. This study aimed to investigate the relationship of the atherogenic index of plasma (AIP) and modified triglyceride-glucose (TyG) indices with digestive diseases.
methodsWe recruited participants aged 45 years or older from the China Health and Retirement Longitudinal Study (CHARLS, 2011 - 2020). The indices assessed included AIP, TyG, triacylglycerol glucose-waist circumference (TyG-WC), the triacylglycerol glucose-waist-to-height ratio (TyG-WHtR), and the triacylglycerol glucose-body mass index (TyG-BMI). We used logistic regression and restricted cubic spline (RCS) analyses to examine the associations between these indices and the incidence of digestive diseases.
resultsA total of 4,453 participants were included in our analysis, 53.3% of whom were female, with an average age of 60 years. The incidence of digestive diseases in middle-aged and older adults was 6.18%. Compared with those in the lowest tertile group, the odds ratios (ORs) with 95% confidence intervals (CIs) for digestive diseases in the highest tertile for AIP, TyG, TyG-WC, TyG-WHtR, and TyG-BMI were 1.452 (1.07-1.972), 1.193 (0.873-1.631), 1.349 (1.044-1.743), 1.5 (1.089-2.068), and 1.312 (0.956-1.799), respectively. Sensitivity analyses confirmed the robustness of the correlations between these indices and digestive diseases.
conclusionOur study revealed that the AIP, TyG-WC, and TyG-WHtR were independently associated with the incidence of digestive diseases. These findings highlight the importance of considering and optimizing metabolic factors in management strategies for digestive diseases.
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