Evidence map›Paper›PMID 39616316›Full record

ArticleBMC musculoskeletal disorders2024

Does body mass index (BMI) significantly influence aseptic loosening in primary total knee arthroplasty? Insights from a long-term retrospective cohort study.

Mohammad Ayati Firoozabadi, Amir Hossein Mafi, Sina Afzal, Shahabaldin Beheshti Fard, Homayoon Khaledian, Ali Bozorgsavoji, Sina Azadnajafabad, Seyed Mohammad Javad Mortazavi

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Article in BMC musculoskeletal disorders, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

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2citing papers in PubMed
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2 · The registry

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3 · Its place in the literature

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2 citing papers in PubMed.

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4 · The record

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5 · Who and what money

Authors and funding

8 authors.

Mohammad Ayati FiroozabadiJoint Reconstruction Research Center, Tehran University of Medical Sciences, Tehran, Iran.
Amir Hossein MafiJoint Reconstruction Research Center, Tehran University of Medical Sciences, Tehran, Iran.
Sina AfzalDepartment of Orthopedic Surgery, School of Medicine, Shahid Beheshti University of Medical Sciences, Tehran, Iran.
Shahabaldin Beheshti FardJoint Reconstruction Research Center, Tehran University of Medical Sciences, Tehran, Iran.
Homayoon KhaledianJoint Reconstruction Research Center, Tehran University of Medical Sciences, Tehran, Iran.
Ali BozorgsavojiJoint Reconstruction Research Center, Tehran University of Medical Sciences, Tehran, Iran.
Sina AzadnajafabadRheumatic and Musculoskeletal Medicine Institute, University of Leeds, Leeds, UK.
Seyed Mohammad Javad MortazaviJoint Reconstruction Research Center, Tehran University of Medical Sciences, Tehran, Iran. smjmort@yahoo.com.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundTotal knee arthroplasty (TKA) offers substantially improved function for patients with severe osteoarthritis, but long-term success can be overshadowed by aseptic loosening, a complication with a multifactorial etiology. This study aims to investigate the association between BMI and the rate of aseptic loosening and other complications in patients undergoing primary TKA.

methodsThis retrospective cohort study examined 354 TKA patients, evenly categorized by BMI (≤ 30 kg/m² and > 30 kg/m²). Demographics, imaging findings, surgical details, and postoperative complications were assessed. Survival for postoperative complications was compared between the two BMI cohorts using Kaplan-Meier analysis.

resultsThe mean age of patients in the BMI ≤ 30 group was 62.44 years, while it was 62.84 years in the BMI > 30 group. The number of patients with short-stemmed tibial components was comparable in the two groups. Out of the total patients, 350 cases showed no loosening, while four experienced aseptic loosening. There was no statistically significant difference in the rate of aseptic loosening or other complications between the two groups.

conclusionWhile a high BMI may contribute to aseptic loosening, it does not appear to be the sole determinant. A multifactorial approach to prevention and management is essential, considering patient-specific factors and prosthetic considerations. Future research with larger cohorts and extended follow-up periods is needed to better elucidate the interplay between BMI and aseptic loosening in patients undergoing TKA.

Indexed as

Arthroplasty, Replacement, KneeBody Mass IndexProsthesis FailureAgedCohort StudiesFemaleFollow-Up StudiesHumansKnee ProsthesisMaleMiddle AgedOsteoarthritis, KneePostoperative ComplicationsRetrospective StudiesTime FactorsAseptic looseningBody mass indexObesitySurgical outcomesTotal knee arthroplasty

Identifiers

PMID39616316
PMCPMC11607931

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