Evidence map›Paper›PMID 39614974›Full record

ArticleInternational microbiology : the official journal of the Spanish Society for Microbiology2025

In vitro activity of nanoliposomal amphotericin B against terbinafine-resistant Trichophyton indotineae isolates.

Mohsen Nosratabadi, Javad Akhtari, Mahmoud Reza Jaafari, Zahra Yahyazadeh, Tahereh Shokohi, Iman Haghani, Pardis Farmani, Robab Ebrahimi Barough, Hamid Badali, Mahdi Abastabar

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Article in International microbiology : the official journal of the Spanish Society for Microbiology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Review
  2. Article
  3. Terbinafine Resistance inAntibiotics (Basel, Switzerland) · 2025
    Review
  4. Formulation, characterization, andCurrent medical mycology · 2025
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Mohsen NosratabadiDepartment of Laboratory Sciences, Sirjan School of Medical Sciences, Sirjan, Iran.
Javad AkhtariDepartment of Medical Nanotechnology, School of Advanced Technologies in Medicine, Mazandaran University of Medical Sciences, Sari, Iran.
Mahmoud Reza JaafariDepartment of Pharmaceutical Nanotechnology, School of Pharmacy, Mashhad University of Medical Sciences, Mashhad, Iran.
Zahra YahyazadehDepartment of Medical Mycology, School of Medicine, Mazandaran University of Medical Sciences, PO Box. 48175-1665, Sari, Iran.
Tahereh ShokohiDepartment of Medical Mycology, School of Medicine, Mazandaran University of Medical Sciences, PO Box. 48175-1665, Sari, Iran.
Iman HaghaniDepartment of Medical Mycology, School of Medicine, Mazandaran University of Medical Sciences, PO Box. 48175-1665, Sari, Iran.
Pardis FarmaniStudent Research Committee, Faculty of Medicine, Mazandaran University of Medical Sciences, Sari, Iran.
Robab Ebrahimi BaroughDepartment of Medical Mycology, School of Medicine, Mazandaran University of Medical Sciences, PO Box. 48175-1665, Sari, Iran.
Hamid BadaliDepartment of Molecular Microbiology and Immunology, South Texas Center for Emerging Infectious Diseases, The University of Texas at San Antonio, San Antonio, TX, USA.
Mahdi AbastabarDepartment of Medical Mycology, School of Medicine, Mazandaran University of Medical Sciences, PO Box. 48175-1665, Sari, Iran. mabastabar@gmail.com.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundThe emergence of resistance in dermatophytes underscores the necessity for developing novel and alternative treatment options.

methodsThe present study aimed to evaluate the in vitro activity of nanoliposomal amphotericin B against a large panel of terbinafine-resistant Trichophyton indotineae isolates. In vitro susceptibility testing of nanoliposomal amphotericin B and comparators against 50 clinical isolates of terbinafine-resistant T. indotineae strains was performed by broth microdilution according to the Clinical and Laboratory Standards Institute (CLSI) M38-A3 document.

resultsThe highest MIC

conclusionsThe study findings revealed that nanoliposomal amphotericin B might be a promising candidate against terbinafine-resistant strains of T. indotineae. However, further studies are required to pave the way for developing novel antifungal compounds to combat fungal resistance.

Indexed as

Amphotericin BAntifungal AgentsDrug Resistance, FungalNaphthalenesTrichophytonHumansMicrobial Sensitivity TestsTerbinafineTineaAmphotericin BAntifungal Agentsliposomal amphotericin BNaphthalenesTerbinafineAmphotericin BIn vitro antifungal activityNanoliposomalTrichophyton indotineae

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.