Evidence map›Paper›PMID 39614741›Full record

ArticleJournal of cutaneous medicine and surgery

Development and Validation of Algorithms to Identify Individuals With Cutaneous Lupus From Healthcare Databases.

Lisa N Guo, Jordan T Said, Michael J Woodbury, Vinod E Nambudiri, Joseph F Merola

Abstract readValidation Study
In one paragraph

Article in Journal of cutaneous medicine and surgery. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
  2. Article
  3. What's New in Cutaneous Lupus Erythematosus: Guidelines, Biologics, and Beyond.The Journal of clinical and aesthetic dermatology · 2026
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Lisa N GuoDepartment of Dermatology, Brigham and Women's Hospital, Boston, MA, USA.ORCID 0000-0003-2152-3567
Jordan T SaidDepartment of Dermatology, Brigham and Women's Hospital, Boston, MA, USA.
Michael J WoodburyHarvard Medical School, Boston, MA, USA.
Vinod E NambudiriDepartment of Dermatology, Brigham and Women's Hospital, Boston, MA, USA.
Joseph F MerolaDivision of Rheumatology, Department of Dermatology and Medicine, UT Southwestern Medical Center, Dallas, TX, USA.

Funding

The Harvard Clinical and Translational Science CenterUL1TR002541 · NCATS · HARVARD MEDICAL SCHOOL · PI NADLER, LEE MARSHALL · 2018 to 2022
$93.0M
NCATS NIH HHS UL1 TR002541
6 · The paper itself

Abstract

backgroundThere are no validated methods to identify individuals with cutaneous lupus erythematosus (CLE) from large databases including claims data and electronic health records, severely limiting the study of the epidemiology of this disease.

objectivesTo develop and validate accurate algorithms to identify individuals with CLE from healthcare records.

methodsTwelve case-finding algorithms were developed based on the International Classification of Diseases (ICD)-10 diagnosis codes, provider specialty, and medication prescription data. To validate performance, algorithms were applied to a test cohort of 300 individuals drawn from a clinical data repository of a multi-institutional healthcare network in Boston, MA. Documentation of a CLE diagnosis by a dermatologist or rheumatologist determined from chart review or supportive biopsy findings was used as the case definition standard. Performance was evaluated based on calculated positive predictive values (PPVs), specificities, and sensitivities of each algorithm.

resultsPPVs ranged from 58.0% to 92.9%. The use of a single diagnosis code for CLE from any provider had poor PPV. The algorithm with the highest PPV (89.0%) while maintaining sensitivity required at least 1 ICD-10 CLE diagnosis code recorded by a dermatologist.

conclusionsUtilizing CLE diagnosis codes and dermatology as the coding provider specialty is a valid method for identifying CLE patients from electronic health records.

Indexed as

AlgorithmsElectronic Health RecordsLupus Erythematosus, CutaneousAdultAgedDatabases, FactualFemaleHumansInternational Classification of DiseasesMaleMiddle Agedcutaneous lupuscutaneous lupus erythematosushealthcare databaseslupus erythematosusvalidation study

Identifiers

PMID39614741
PMCPMC11979305

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.