Evidence map›Paper›PMID 39614709›Full record

ArticleSmall (Weinheim an der Bergstrasse, Germany)2025

Optomagnetic Micromirror Arrays for Mapping Large Area Stiffness Distributions of Biomimetic Materials.

Hsin Lan, Xing Haw Marvin Tan, Minh-Tam Tran Le, Hao-Yu Chien, Ruoda Zheng, Amy C Rowat, Michael A Teitell, Pei-Yu Chiou

Abstract read
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In one paragraph

Article in Small (Weinheim an der Bergstrasse, Germany), 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Hsin LanDepartment of Mechanical and Aerospace Engineering, University of California Los Angeles, Los Angeles, CA, 90095, USA.ORCID https://orcid.org/0009-0007-8715-7340
Xing Haw Marvin TanDepartment of Mechanical and Aerospace Engineering, University of California Los Angeles, Los Angeles, CA, 90095, USA.
Minh-Tam Tran LeDepartment of Bioengineering, University of California Los Angeles, Los Angeles, CA, 90095, USA.
Hao-Yu ChienDepartment of Electrical and Computer Enigeering, University of California Los Angeles, Los Angeles, CA, 90095, USA.
Ruoda ZhengDepartment of Mechanical and Aerospace Engineering, University of California Los Angeles, Los Angeles, CA, 90095, USA.
Amy C RowatDepartment of Bioengineering, University of California Los Angeles, Los Angeles, CA, 90095, USA.
Michael A TeitellDepartment of Bioengineering, University of California Los Angeles, Los Angeles, CA, 90095, USA.
Pei-Yu ChiouDepartment of Mechanical and Aerospace Engineering, University of California Los Angeles, Los Angeles, CA, 90095, USA.

Funding

SPOTs: Optical Technologies for Instantly Quantifying Multicellular Response ProfilesR01GM127985 · NIGMS · UNIVERSITY OF CALIFORNIA LOS ANGELES · PI CHIOU, PEI-YU, TEITELL, MICHAEL A · 2020 to 2023
$1.7M
DBI 2345571National Science Foundation CMMI 2029454NIGMS NIH HHS R01 GM127985NIH HHS R01GM127985NSF BRITE CMMI-2135747
6 · The paper itself

Abstract

A new device termed "Optomagnetic Micromirror Arrays" (OMA) is demonstrated capable of mapping the stiffness distribution of biomimetic materials across a 5.1 mm × 7.2 mm field of view with cellular resolution. The OMA device comprises an array of 50 000 magnetic micromirrors with optical grating structures embedded beneath an elastic PDMS film, with biomimetic materials affixed on top. Illumination of a broadband white light beam onto these micromirrors results in the reflection of microscale rainbow light rays on each micromirror. When a magnetic field is applied, it causes each micromirror to tilt differently depending on the local stiffness of the biomimetic materials. Through imaging these micromirrors with low N.A. optics, a specific narrow band of reflection light rays from each micromirror is captured. Changing a micromirror's tilt angle also alters the color spectrum it reflects back to the imaging system and the color of the micromirror image it represents. As a result, OMA can infer the local stiffness of the biomimetic materials through the color change detected on each micromirror. OMA offers the potential for high-throughput stiffness mapping at the tissue-level while maintaining spatial resolution at the cellular level.

Indexed as

magnetic anisotropyMEMSmicromirroroptical diffraction

Identifiers

PMID39614709
PMCPMC11710979

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.