Evidence map›Paper›PMID 39614354›Full record

ArticleJournal of neuroengineering and rehabilitation2024

A one-year follow-up case series on gait analysis and patient-reported outcomes for persons with unilateral and bilateral transfemoral amputations undergoing direct skeletal fixation.

Diana Toderita, Tiereny McGuire, Alice M Benton, Charles Handford, Arul Ramasamy, Paul Hindle, Anthony M J Bull, Louise McMenemy

Abstract read
In one paragraph

Article in Journal of neuroengineering and rehabilitation, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Self-reported health outcomes and medical complications at 6- and 8-year follow-up after direct skeletal fixation in individuals with bilateral transfemoral amputations.International journal of rehabilitation research. Internationale Zeitschrift fur Rehabilitationsforschung. Revue internationale de recherches de readaptation · 2025
    Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Diana ToderitaDepartment of Bioengineering, Imperial College London, London, UK. diana.toderita15@imperial.ac.uk.
Tiereny McGuireDepartment of Bioengineering, Imperial College London, London, UK.
Alice M BentonDepartment of Bioengineering, Imperial College London, London, UK.
Charles HandfordDepartment of Bioengineering, Imperial College London, London, UK.
Arul RamasamyDepartment of Bioengineering, Imperial College London, London, UK.
Paul HindleSt. Paul's Hospital, Vancouver, Canada.
Anthony M J BullDepartment of Bioengineering, Imperial College London, London, UK.
Louise McMenemyDepartment of Bioengineering, Imperial College London, London, UK.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundDirect skeletal fixation, a surgical technique enabling the attachment of an external prosthesis directly to the bone through a percutaneous implant, offers an enticing solution for patients with lower limb amputations facing socket-related issues. However, understanding of its impact on musculoskeletal function remains limited.

methodsThis study compares pre- and 1-year post-osseointegration surgery outcomes, focusing on patient-reported measures and musculoskeletal system function during level-ground walking. Two participants with unilateral transfemoral amputations and two participants with bilateral transfemoral amputations completed the questionnaire for transfemoral amputations (Q-TFA) and underwent gait analysis. Musculoskeletal modelling simulations were conducted.

resultsResults showed improved Q-TFA scores for all participants. Participants showed reduced amputated limb peak hip extension angles, flexion torques and contact forces at the push-off phase of the gait cycle. Post-operatively, hip adduction angles and abduction moments increased, indicating more natural gait patterns. Whilst one participant demonstrated increased post-operative walking speed, others walked more slowly.

conclusionsThe study revealed diverse adaptation patterns after one year in individuals with transfemoral amputations transitioning to bone-anchored prostheses. Additional longer-term data is necessary to enable generalization and clinical implications of these results.

Indexed as

Amputation, SurgicalGait AnalysisPatient Reported Outcome MeasuresAdultAmputeesArtificial LimbsBiomechanical PhenomenaBone-Anchored ProsthesisFemaleFemurFollow-Up StudiesGaitHumansMaleMiddle AgedOsseointegrationGait analysisMusculoskeletal modellingOsseointegrated prosthesesTransfemoral amputation

Identifiers

PMID39614354
PMCPMC11606069

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.