SynthesisJournal of orthopaedic surgery and research2024
Risk factors for deep surgical site infections following orthopedic trauma surgery: a meta-analysis and systematic review.
Synthesis in Journal of orthopaedic surgery and research, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers, 1 of them a synthesis that pooled it.
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Who cites it
14 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Topical antibiotic powder reduces fracture-related infections in pelvic and lower limb fractures: a systematic review and meta-analysis.European journal of orthopaedic surgery & traumatology : orthopedie traumatologie · 2026Pooled it
- Multifunctional TPU-HAp/HA-TiOInternational journal of pharmaceutics: X · 2026Article
- Ocular Clues in Musculoskeletal Disorders: A Narrative Review for Orthopaedic Specialists.Journal of the American Academy of Orthopaedic Surgeons. Global research & reviews · 2026Review
- A retrospective comparative study of intraoperative fluoroscopy and postoperative radiography for measuring mounting parameters of the taylor spatial frame in tibial fractures.Journal of orthopaedic surgery and research · 2026Article
- Distribution of putative SSI risk factors in adults undergoing open reduction and fixation of long bone fracture.European journal of orthopaedic surgery & traumatology : orthopedie traumatologie · 2026Observational
- Benchmarking Early Unplanned Trauma Re-operations: A Five-Year Institutional Review of 7,400 Orthopaedic Cases.Cureus · 2026Article
- Use of intraoperative vancomycin powder and its effects on the incidence of surgical site infection in orthopaedic trauma: a systematic review with meta-analysis.OTA international : the open access journal of orthopaedic trauma · 2026Article
- Direct economic and temporal burdens of nosocomial infections on orthopaedic patients: a nested case-control study.Epidemiology and infection · 2026Article
- Prevention and Treatment of Surgical Site Infections in Orthopaedic Surgery: An Italian Delphi Consensus on Risk Stratification and Wound Irrigation Strategies.Journal of clinical medicine · 2026Review
- Predictive value of a preoperative computed tomography-derived perifracture soft-tissue envelope index for fracture-related infection after open reduction and internal fixation of tibial plateau fractures.Frontiers in medicine · 2026Article
- Microbiologic analysis of 140 patients undergoing revision total knee arthroplasty due to periprosthetic joint infection and aseptic loosening: droplet digital PCR analysis.Journal of orthopaedic surgery and research · 2025Article
- Nomogram Development and Feature Selection Strategy Comparison for Predicting Surgical Site Infection After Lower Extremity Fracture Surgery.Medicina (Kaunas, Lithuania) · 2025Article
- Risk Factors and Clinical Outcomes of Deep Surgical Site Infections in Trauma Patients: A National Database Analysis.Healthcare (Basel, Switzerland) · 2025Article
- Mid-term results after DAIR for patients with acute periprosthetic joint infections of the hip or knee.Journal of orthopaedic surgery and research · 2025Article
Corrections and comments
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Authors and funding
5 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
objectiveWe conducted this meta-analysis to explore the risk factors and incidence of deep surgical site infections (DSSIs) after orthopaedic trauma surgery.
methodsA systematic search was conducted across various databases, including MEDLINE, Embase, Cochrane Library, and Web of Science, for studies examining risk factors associated with DSSIs after bone trauma procedures. The search concluded on September 1, 2024. Data analysis was performed using Stata 15.0.
resultsAmong 2,722 publications screened, 16 studies that met the eligibility criteria were included in the analysis, involving a total of 22,318 patients, of whom 894 experienced DSSIs. The meta-analysis revealed a combined incidence of deep infections after orthopedic trauma surgery at [ES = 6.7%, 95% CI (5.1%-8.2%)]. Risk factors identified included male gender [OR = 1.99, 95% CI (1.39, 2.86), p < 0.0001], current smoking status [OR = 2.60, 95% CI (1.85, 3.65), p < 0.0001], open injuries [OR = 3.17, 95% CI (1.72, 5.85), p < 0.0001], a BMI greater than 26.0 kg/m
conclusionThis study identifies key risk factors for DSSI following orthopedic trauma surgery, addressing a gap in the existing literature and offering some insights for clinical decision-making. To mitigate the risk of DSSI, clinical practice should encourage patients to lose weight and quit smoking prior to surgery, optimize surgical procedures, and improve wound management strategies. Future research should aim to standardize follow-up durations and further refine the classification of risk factors, in order to validate and expand on the conclusions of this study.
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