Trial reportBMC complementary medicine and therapies2024
The effect of self-administered acupressure on pain severity and sleep quality of patients with knee osteoarthritis: a randomized controlled trial.
Trial report in BMC complementary medicine and therapies, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
4 citing papers in PubMed.
- Nonlinear relationship between sleep midpoint and osteoarthritis: a cross-sectional study in US adults.Clinical rheumatology · 2026Article
- Pregabalin plus celecoxib for knee osteoarthritis: impact on pain, knee function recovery, and inflammatory biomarkers.American journal of translational research · 2026Article
- Effects of nocturnal melatonin-based tissue-bone homeostasis manipulation at varying time points on pain and central mechanisms in individuals with knee osteoarthritis: a randomized controlled trial.Frontiers in bioengineering and biotechnology · 2026Article
- Acupressure for Sleep, Mental Health, and Quality of Life in Hemodialysis Patients: A Systematic Review and Meta-Analysis.Nature and science of sleep · 2026Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundPain in the knee joint area and reduced sleep quality are prevalent symptoms of knee osteoarthritis. This study examines the impact of self-administered acupressure on pain severity and sleep quality in patients with knee osteoarthritis.
methodsIn this trial conducted in 2023, 126 patients were enrolled. They completed a demographic characteristics form, the Visual Analogue Scale (VAS), and the Pittsburgh Sleep Quality Index (PSQI). Afterward, they were randomly allocated to three groups: acupressure, sham, and control. While the control group received routine care, patients in the acupressure and sham groups were instructed to apply pressure on selected acupoints daily for one minute for a duration of one month. All participants completed the PSQI and the VAS one month after the intervention began and one month after it ended. Data analysis involved Fisher's exact tests, chi-square, Kruskal-Wallis, and one-way ANOVA tests. Also, per-protocol analyses were conducted with linear mixed-effects models.
resultsNo significant effects associated with group allocation were observed on pain VAS scores in acupressure and sham groups compared to the control group. However, participants in the acupressure group showed a significant decrease in pain VAS scores as time progressed. PSQI scores significantly decreased over time. Interaction effects showed that PSQI scores decreased more in the acupressure than in the control group over time. Finally, PSQI scores in the acupressure group demonstrated a significant decrease from pretest to follow-up, while no significant change was observed over time in the sham group.
conclusionsSelf-administered acupressure may be useful in improving sleep quality in patients with knee osteoarthritis. This work may be informative in developing acupressure interventions with more effective outcomes in future research.
trial registrationThis trial is registered on the Iranian Registry of Clinical Trials website with the identifier IRCT20211221053475N1 (Date: 10/01/2022).
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